Evidence map›Paper›PMID 39744690›Full record

ArticleTheranostics2025

Inhibition of nitric oxide synthase transforms carotid occlusion-mediated benign oligemia into

Ha Kim, Jinyong Chung, Jeong Wook Kang, Dawid Schellingerhout, Soo Ji Lee, Hee Jeong Jang, Inyeong Park, Taesu Kim, Dong-Seok Gwak, Ji Sung Lee and 8 more

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Genetic determinants of insufficiency of the collateral circulation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ha KimDepartment of neurology, Dongguk University Ilsan Hospital, Goyang 10326, Republic of Korea.
Jinyong ChungMedical Science Research Center, Dongguk University, Goyang 10326, Republic of Korea.
Jeong Wook KangDepartment of neurology, Dongguk University Ilsan Hospital, Goyang 10326, Republic of Korea.
Dawid SchellingerhoutDepartments of Neuroradiology and Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
Soo Ji LeeGenome & Health Big Data Laboratory, Department of Public Health, Graduate School of Public Health, Seoul National University, Seoul 08826, Republic of Korea.
Hee Jeong JangDepartment of neurology, Dongguk University Ilsan Hospital, Goyang 10326, Republic of Korea.
Inyeong ParkDepartment of neurology, Dongguk University Ilsan Hospital, Goyang 10326, Republic of Korea.
Taesu KimDepartment of neurology, Dongguk University Ilsan Hospital, Goyang 10326, Republic of Korea.
Dong-Seok GwakDepartment of neurology, Dongguk University Ilsan Hospital, Goyang 10326, Republic of Korea.
Ji Sung LeeClinical Research Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Sung-Ha HongCenter for Translational Neuromedicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14620, USA.
Kang-Hoon JeDepartment of neurology, Dongguk University Ilsan Hospital, Goyang 10326, Republic of Korea.
Hee-Joon BaeDepartment of Neurology and Cerebrovascular Center, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea.
Joohon SungGenome & Health Big Data Laboratory, Department of Public Health, Graduate School of Public Health, Seoul National University, Seoul 08826, Republic of Korea.
Eng H LoNeuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
James FaberDepartment of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC 27599, USA.
Cenk AyataNeurovascular Research Unit, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Dong-Eog KimDepartment of neurology, Dongguk University Ilsan Hospital, Goyang 10326, Republic of Korea.

Funding

Targeting the Pial Collateral Circulation for Mitigation of Cerebral IschemiaR01NS083633 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZHANG, HUA · 2013 to 2023
$4.5M
NINDS NIH HHS R01 NS083633
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cerebral InfarctionDisease Models, AnimalMice, Inbred BALB CMice, Inbred C57BLNG-Nitroarginine Methyl EsterNitric Oxide SynthaseAgedAnimalsEnzyme InhibitorsFemaleHumansMaleMiceMiddle AgedStrokeEnzyme InhibitorsNG-Nitroarginine Methyl EsterNitric Oxide Synthasecarotid artery occlusioncerebral infarctionnitric oxide synthaseoligemiastroke

Identifiers

PMID39744690
PMCPMC11671383

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.