Evidence map›Paper›PMID 39745436›Full record

ArticleJournal of virology2025

Characteristics of viral ovarian tumor domain protease from two emerging orthonairoviruses and identification of Yezo virus human infections in northeastern China as early as 2012.

Zi-Yun Chen, Jie Zhang, Pei-Jun He, Tao Xiong, Dai-Yun Zhu, Wen-Jie Zhu, Xue-Bing Ni, Li-Feng Du, Qian Wang, Ya-Wei Zhang and 13 more

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Pathogenicity of a novel orthonairovirus, Iwanai Valley virus, in mice.The Journal of veterinary medical science · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Zi-Yun Chen *School of Public Health of Fujian Medical University, Fuzhou, Fujian, China.ORCID 0009-0008-5850-4363
Jie Zhang *State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Pei-Jun He *State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Tao Xiong *State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Dai-Yun Zhu *State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Wen-Jie ZhuState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Xue-Bing NiState Key Laboratory of Emerging Infectious Diseases and Centre of Influenza Research, School of Public Health, University of Hong Kong, Hong Kong, China.
Li-Feng DuState Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, Shanghai, China.
Qian WangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Ya-Wei ZhangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Luo-Yuan XiaState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Dong-Sheng ChenState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Liang-Jing LiState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Ming-Zhu ZhangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Xiao Ming CuiState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Tian-Hong WangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Juan WangState Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, Shanghai, China.
Zhenfei WangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Tian-Feng AnDepartment of Toxicology and Health Inspection and Quarantine, School of Public Health, Tianjin Medical University, Tianjin, Tianjin, China.
Wu-Chun CaoState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
Xiao-Hua LiuSchool of Public Health and Health Management, Gannan Medical University, Ganzhou, Jiangxi, China.ORCID 0009-0008-2516-7313
En-Jiong HuangSchool of Public Health of Fujian Medical University, Fuzhou, Fujian, China.ORCID 0009-0005-2770-1928
Na JiaState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.ORCID 0000-0003-0532-7064

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging tick-borne orthonairovirus infections pose a growing global concern, with limited understanding of the viral ovarian tumor-like cysteine proteases (vOTUs) encoded by novel orthonairoviruses. These vOTUs, a group of deubiquinylases (DUBs), disrupt the innate immune response. Yezo virus (YEZV), a recently discovered pathogenic orthonairovirus, was first reported in Japan in 2021. In this study, we successfully isolated and identified YEZV and a new orthonairovirus, Jiànchuān tick virus (JCTV), from

Indexed as

Cysteine ProteasesViral ProteinsAnimalsChinaFemaleHumansIxodesNairovirusPhylogenyCysteine ProteasesViral Proteinsorthonairovirusovarian tumor-like cysteine proteaseretrospective surveillancetick-bite patients

Identifiers

PMID39745436
PMCPMC11852922

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.