Evidence map›Paper›PMID 39745601›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2025

Biology of Hox Genes: Questions and Technological Challenges.

Sudheesh Allikka Parambil, Bony De Kumar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Toward a cell-type-specific lung HOX code.Frontiers in cell and developmental biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sudheesh Allikka ParambilDepartment of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT, USA.
Bony De KumarYale Center For Genome Analysis , West Haven, CT, USA. Bony.dekumar@yale.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hox genes are crucial in determining segmentation identity in developing embryos, which ultimately sets an anteroposterior body axis. Over a century of research has discovered the fundamentals of the Hox gene and protein function in animal development and diseases. However, there are still fundamental questions about the specificity of HOX function. This chapter discusses many unknowns about Hox genes and how modern technologies can overcome technical limitations. We have also addressed these questions to gain a better understanding of the roles of these genes.

Indexed as

Genes, HomeoboxAnimalsBody PatterningGene Expression Regulation, DevelopmentalHomeodomain ProteinsHumansHomeodomain ProteinsEvolutionary conservationExpressionFunctional specificityHox genesTranscriptional specificity

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.