Evidence map›Paper›PMID 39745648›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

StarTrack: Mapping Cellular Fates with Inheritable Color Codes.

M Figueres-Oñate, Jorge García-Marqués, A C Ojalvo-Sanz, Laura López-Mascaraque

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

M Figueres-OñateInstituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid, Spain. mfigueres@cajal.csic.es.ORCID 0000-0001-8010-8668
Jorge García-MarquésInstituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid, Spain.ORCID 0000-0001-5688-566X
A C Ojalvo-SanzInstituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid, Spain.ORCID 0000-0001-8783-0952
Laura López-MascaraqueInstituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid, Spain. mascaraque@cajal.csic.es.ORCID 0000-0002-7154-5687

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

StarTrack is a powerful multicolor genetic tool designed to unravel cellular lineages arising from neural progenitor cells (NPCs). This innovative technique, based on retrospective clonal analysis and built upon the PiggyBac system, creates a unique and inheritable "color code" within NPCs. Through the stochastic integration of 12 distinct plasmids encoding six fluorescent proteins, StarTrack enables precise and comprehensive tracking of cellular fates and progenitor potentials. The versatility of this tool is further enhanced by the potential of combining multiple promoters. Whether through the use of fluorescent integrable constructs or driving the expression of the PiggyBac transposase, StarTrack broadens the horizons for lineage tracing from progenitors of multiple origins.StarTrack revolutionized our understanding of cellular origins and lineages, offering an invaluable resource for researchers in the field of neural development and lineage tracing. This protocol provides a comprehensive overview of the technique's capabilities and applications, shedding light on its significance within the scientific community.

Indexed as

Cell LineageNeural Stem CellsAnimalsCell DifferentiationHumansLuminescent ProteinsMicePlasmidsLuminescent ProteinsCell fateClonal analysisGenetic taggingIn utero electroporationLineage tracingProgenitor potentialStarTrack

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.