Evidence map›Paper›PMID 39746750›Full record

ArticleRNA (New York, N.Y.)2025

Global analysis by LC-MS/MS of

Stanislav Stejskal, Veronika Rájecká, Helena Covelo-Molares, Ketty Sinigaglia, Květoslava Brožinová, Linda Kašiarová, Michaela Dohnálková, Paul Eduardo Reyes-Gutierrez, Hana Cahová, Liam P Keegan and 2 more

Abstract read
In one paragraph

Article in RNA (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Epitranscriptomic alterations induced by environmental toxins: implications for RNA modifications and disease.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stanislav Stejskal *Central European Institute of Technology (CEITEC), Masaryk University, Brno 62500, Czech Republic.ORCID 0000-0003-0971-343X
Veronika Rájecká *Central European Institute of Technology (CEITEC), Masaryk University, Brno 62500, Czech Republic.ORCID 0000-0001-5211-0365
Helena Covelo-Molares *Central European Institute of Technology (CEITEC), Masaryk University, Brno 62500, Czech Republic.ORCID 0000-0001-8476-0880
Ketty SinigagliaCentral European Institute of Technology (CEITEC), Masaryk University, Brno 62500, Czech Republic.ORCID 0000-0001-5368-6307
Květoslava BrožinováCentral European Institute of Technology (CEITEC), Masaryk University, Brno 62500, Czech Republic.
Linda KašiarováCentral European Institute of Technology (CEITEC), Masaryk University, Brno 62500, Czech Republic.ORCID 0000-0002-8701-3554
Michaela DohnálkováCentral European Institute of Technology (CEITEC), Masaryk University, Brno 62500, Czech Republic.ORCID 0009-0008-8241-7171
Paul Eduardo Reyes-GutierrezInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic.ORCID 0000-0002-6325-8936
Hana CahováInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic.ORCID 0000-0002-4986-7858
Liam P KeeganCentral European Institute of Technology (CEITEC), Masaryk University, Brno 62500, Czech Republic.ORCID 0000-0001-7915-5790
Mary A O'ConnellCentral European Institute of Technology (CEITEC), Masaryk University, Brno 62500, Czech Republic stepanka.vanacova@ceitec.muni.cz mary.oconnell@ceitec.muni.cz.ORCID 0000-0003-3844-6174
Štěpánka VaňáčováCentral European Institute of Technology (CEITEC), Masaryk University, Brno 62500, Czech Republic stepanka.vanacova@ceitec.muni.cz mary.oconnell@ceitec.muni.cz.ORCID 0000-0001-8807-0684

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The precise and unambiguous detection and quantification of internal RNA modifications represents a critical step for understanding their physiological functions. The methods of direct RNA sequencing are quickly developing allowing for the precise location of internal RNA marks. This detection is, however, not quantitative and still presents detection limits. One of the biggest remaining challenges in the field is still the detection and quantification of m

Indexed as

AdenosineInosineRNA, MessengerAlkB Homolog 5, RNA DemethylaseAlpha-Ketoglutarate-Dependent Dioxygenase FTOChromatography, LiquidHEK293 CellsHumansLiquid Chromatography-Mass SpectrometryMethylationRNA Processing, Post-TranscriptionalTandem Mass SpectrometryAdenosineALKBH5 protein, humanAlkB Homolog 5, RNA DemethylaseAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanInosineN-methyladenosineRNA, MessengerADARadenosine methylationALKBH5FTOinosineRNA editing

Identifiers

PMID39746750
PMCPMC11912911

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.