ArticleScientific reports2025
Correlation analysis of the triglyceride-glucose index and related parameters in metabolic dysfunction-associated fatty liver disease.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Associations of TyG-related indices with NAFLD-related outcomes: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Pooled it
- Clinical Utility of the Triglyceride-Glucose Index in Assessing Hepatic Steatosis Severity Within the MASLD Spectrum.Diagnostics (Basel, Switzerland) · 2026Article
- The relationship between triglyceride-glucose index, triglyceride-glucose-body mass index, and the severity of hepatic steatosis and liver fibrosis in patients with MASLD: a cross-sectional study.Frontiers in nutrition · 2026Article
- Cumulative Triglyceride-Glucose Index and Risk of Metabolic Dysfunction-Associated Fatty Liver Disease: Findings from the Kailuan Cohort.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Ability of triglyceride-glucose indices to predict metabolic dysfunction associated with steatotic liver disease in pediatric obesity.Journal of pediatric gastroenterology and nutrition · 2025Article
- Machine learning-based identification of biochemical markers to predict hepatic steatosis in patients at high metabolic risk.World journal of gastroenterology · 2025Article
- Fatty Liver Index vs. Biochemical-Anthropometric Indices: Diagnosing Metabolic Dysfunction-Associated Steatotic Liver Disease with Non-Invasive Tools.Diagnostics (Basel, Switzerland) · 2025Article
- Predicting the risk of metabolic-associated fatty liver disease in the elderly population in China: construction and evaluation of interpretable machine learning models.Frontiers in medicine · 2025Article
- Triglyceride-glucose index associated with anthropometric parameters: Early markers in the progression of nonalcoholic fatty liver disease.Hepatology forum · 2025Article
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7 authors.
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Abstract
This study aimed to investigate the correlation and predictive value of TyG and related parameters with metabolic dysfunction-associated fatty liver disease (MAFLD) MAFLD. This study retrospectively included individuals who underwent health examinations and abdominal ultrasound from July 2021 to June 2024 at the Affiliated Hospital of Southwest Medical University, Sichuan Province, China. A total of 71,299 subjects' clinical and laboratory data were extracted, the correlation between TyG and related parameters and MAFLD was analyzed via univariate and multivariate logistic regression methods, and the nonlinear relationship between the TyG index and the risk of MAFLD was explored via restricted cubic spline (RCS) analysis. The predictive value of TyG and related parameters for MAFLD was assessed using the receiver operating characteristic (ROC) curves and the area under the ROC curve (AUC). TyG and related parameters were positively correlated with MAFLD, and the results remained unchanged after adjustment for the corresponding parameters. RCS analysis revealed a significant dose‒response relationship between TyG and related parameters and MAFLD. ROC curve analysis revealed AUC values of 0.83 (0.82-0.83), 0.92 (0.91-0.92), 0.90 (0.90-0.91), and 0.87 (0.87-0.88) for TyG, TyG-BMI, TyG-WC, and TyG-WHR, respectively. Subgroup analyses revealed that the TyG index and related parameters had greater predictive value in the female, younger, and BMI < 23.7 populations.
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