Evidence map›Paper›PMID 39749266›Full record

ArticleFrontiers in clinical diabetes and healthcare2024

Neonatal body composition, salivary feeding gene expression, and feeding outcomes in infants of diabetic mothers.

Dara Azuma, Yvette Penner, Tomoko Kaneko-Tarui, Taysir Mahmoud, Janis L Breeze, Angie Rodday, Perrie O'Tierney-Ginn, Jill L Maron

Abstract read
In one paragraph

Article in Frontiers in clinical diabetes and healthcare, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dara AzumaMother Infant Research Institute at Tufts Medical Center, Boston, MA, United States.
Yvette PennerFrances Stern Nutrition Center at Tufts Medical Center, Boston, MA, United States.
Tomoko Kaneko-TaruiMother Infant Research Institute at Tufts Medical Center, Boston, MA, United States.
Taysir MahmoudMother Infant Research Institute at Tufts Medical Center, Boston, MA, United States.
Janis L BreezeClinical and Translational Science Program, Tufts University Graduate School of Biomedical Sciences, Boston, MA, United States.
Angie RoddayClinical and Translational Science Program, Tufts University Graduate School of Biomedical Sciences, Boston, MA, United States.
Perrie O'Tierney-GinnMother Infant Research Institute at Tufts Medical Center, Boston, MA, United States.
Jill L MaronMother Infant Research Institute at Tufts Medical Center, Boston, MA, United States.

Funding

CTSA Graduate ProgramTL1TR002546 · NCATS · TUFTS UNIVERSITY BOSTON · PI KENT, DAVID M · 2018 to 2022
$4.2M
NCATS NIH HHS TL1 TR002546
6 · The paper itself

Abstract

Introduction: Infants of diabetic mothers (IDMs) may exhibit decreased oral intake, requiring nasogastric feedings and prolonged hospitalization. The objective of this study was to explore whether saliva serves as an informative biofluid for detecting expression of hunger signaling and energy homeostasis modulator genes and to perform exploratory analyses examining expression profiles, body composition, and feeding outcomes in late preterm and term IDMs and infants born to mothers with normoglycemia during pregnancy. Methods: In this prospective cohort pilot study, infants born at ≥ 35 weeks' gestation to mothers with gestational or type II diabetes (IDM cohort) and normoglycemic mothers (control cohort) were recruited. The presence of known hunger signaling genes: 5'AMP-activated protein kinase ( Results: Twenty-three infants in the IDM cohort and 22 infants in the control cohort were recruited. Discussion: Non-invasive assessment of hunger signaling and energy homeostasis gene expression is possible through neonatal salivary analysis. This pilot study lays the foundation for a larger scale study to further investigate the link between

Indexed as

body compositionfeedingmaternal diabetesneonatalsaliva

Identifiers

PMID39749266
PMCPMC11693610

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.