Evidence map›Paper›PMID 39749782›Full record

ReviewThe Kaohsiung journal of medical sciences2025

Aptasensor-based point-of-care detection of cardiac troponin biomarkers for diagnosis of acute myocardial infarction.

Tharmaraj Vairaperumal, Ping-Yen Liu

Abstract readReview
In one paragraph

Review in The Kaohsiung journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tharmaraj VairaperumalInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ping-Yen LiuInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.ORCID https://orcid.org/0000-0002-3643-5204

Funding

Ministry of Science and Technology, Taiwan 111-2314-B-006-017-MY3National Health Research Institutes NHRI-112A1-CACO-02232311
6 · The paper itself

Abstract

Acute myocardial infarction (AMI) represents a critical health challenge characterized by a significant reduction in blood flow to the heart, leading to high rates of mortality and morbidity. Cardiac troponins, specifically cardiac troponin I and cardiac troponin T, are essential proteins involved in cardiac muscle contraction and serve as vital biomarkers for the diagnosis of AMI. Aptasensors utilize synthetic aptamers or peptides with high affinity for specific biomarkers and offer a promising approach for integration into portable, user-friendly point-of-care (POC) applications. This review explores recent advances in POC aptasensor-based platforms for the rapid detection of cardiac troponin biomarkers. Furthermore, this review addresses current challenges and potential future directions in the development of aptasensor. Also, it highlights their potential to improve timely and accurate diagnosis in clinical and emergency settings.

Indexed as

Aptamers, NucleotideBiosensing TechniquesMyocardial InfarctionPoint-of-Care SystemsTroponin ITroponin TBiomarkersHumansAptamers, NucleotideBiomarkersTroponin ITroponin Tacute myocardial infarctionaptasensorbiomarkerscardiac troponinspoint‐of‐care

Identifiers

PMID39749782
PMCPMC11924801

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.