Evidence map›Paper›PMID 39751819›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2025

Resveratrol polysaccharide is less cytotoxicity and inhibits UVA-, UVB-, and tertiary-butyl hydroperoxide-induced injury in human keratinocytes.

Yasukazu Saitoh, Shizuka Kanawa, Tsugumi Nohara, Ryoko Yamaguchi, Arisa Wakita, Chinatsu Ikeda, Hiroki Hamada

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yasukazu SaitohDepartment of Life Sciences, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, Shobara, Japan. ysaito@pu-hiroshima.ac.jp.ORCID 0000-0002-6288-7634
Shizuka KanawaDepartment of Life Sciences, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, Shobara, Japan.
Tsugumi NoharaDepartment of Life Sciences, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, Shobara, Japan.
Ryoko YamaguchiDepartment of Life Sciences, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, Shobara, Japan.
Arisa WakitaDepartment of Life Sciences, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, Shobara, Japan.
Chinatsu IkedaDepartment of Life and Environmental Sciences, Faculty of Bioresource Sciences, Prefectural University of Hiroshima, Nanatsuka 5562, Shobara, Hiroshima, 727-0023, Japan.
Hiroki HamadaMeisterbio Co., Ltd., Okayama, Japan.

Funding

JSPS KAKENHI JP20K11627 and JP23K10922
6 · The paper itself

Abstract

Natural stilbene compounds, such as resveratrol and pterostilbene, have been focused on owing to their diverse biological activities associated with antioxidant, anti-inflammatory, and anti-aging properties. However, their low water solubility limits their advanced applications. In this study, we investigated the protective effects of selected stilbene compounds (resveratrol, oxyresveratrol, gnetol, piceatannol, and pterostilbene) and their water-soluble derivatives (piceid, resveratrol polysaccharide, pterostilbene trisaccharide, and pterostilbene polysaccharide) against UVA-, UVB irradiation, tertiary-butyl hydroperoxide (t-BuOOH)- and hydrogen peroxide (H

Indexed as

AntioxidantsKeratinocytesPolysaccharidesStilbenestert-ButylhydroperoxideUltraviolet RaysCell SurvivalHumansHydrogen PeroxideReactive Oxygen SpeciesResveratrolAntioxidantsHydrogen PeroxidePolysaccharidesReactive Oxygen SpeciesResveratrolStilbenestert-ButylhydroperoxideKeratinocyteLipid peroxidationReactive oxygen speciesResveratrol polysaccharideStilbene compoundUV

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.