Evidence map›Paper›PMID 39752016›Full record

ArticleMarine biotechnology (New York, N.Y.)2025

Association of Single Nucleotide Polymorphisms in Cysteamine Dioxygenase Gene with Taurine Content in Oyster Crassostrea gigas.

Shiqing Sun, Ning Kong, Xiang Li, Chunyu Jiang, Mingyu Xue, Lingling Wang, Linsheng Song

Abstract read
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In one paragraph

Article in Marine biotechnology (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shiqing SunLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China.
Ning KongLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China. kongning@dlou.edu.cn.
Xiang LiLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China.
Chunyu JiangLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China.
Mingyu XueLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China.
Lingling WangLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China. wanglingling@dlou.edu.cn.
Linsheng SongLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China.

Funding

China Agriculture Research System CARS-49Dalian High Level Talent Innovation Support Program 2022RG14
6 · The paper itself

Abstract

The Pacific oyster Crassostrea gigas is rich in taurine, a conditionally essential amino acid functioning in anti-oxidation, anti-inflammation, anti-aging, osmoregulation, and neuromodulation. Breeding oyster varieties with enhanced taurine content is significant to meet people's demand for high-quality oysters. In the present study, polymorphisms in the oyster cysteamine dioxygenase (CgADO) gene that encodes the central enzyme of the cysteamine pathway for taurine synthesis were investigated, and their association with taurine content was assessed in the Changhai (CH) and Qinhuangdao (QHD) populations. A total of 47 single nucleotide polymorphism (SNP) loci were identified in the exonic region of CgADO through Sanger sequencing, with a synonymous SNP (c.415T>C) showing a significant association with taurine content. Oysters with the CT genotype at c.415T>C exhibited higher taurine content than those with the TT genotype (p < 0.05). Moreover, a significant difference in the CgADO mRNA expression was observed between oysters with different genotypes, with higher expression in the CT genotype compared to the TT genotype (p < 0.001). These findings indicate the potential influence of CgADO polymorphisms on taurine content in C. gigas and provide candidate functional markers for the selective breeding of oyster varieties with improved taurine levels.

Indexed as

CrassostreaPolymorphism, Single NucleotideTaurineAnimalsGenotypeTaurineCrassostrea gigasCysteamine dioxygenaseSNPTaurine

Identifiers

PMID39752016

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.