Evidence map›Paper›PMID 39754070›Full record

SynthesisBMC infectious diseases2025

Prevalence of intestinal parasites and Helicobacter pylori co-infection in people with gastrointestinal symptoms in Africa: a systematic review and meta-analysis.

Yenesew Mihret Wondmagegn, Getu Girmay, Gashaw Azanaw Amare, Muluneh Assefa, Mebratu Tamir, Zufan Yiheyis Abriham, Abebaw Setegn

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Clinical and experimental gastroenterology · 2026
    Review
  4. Article
  5. Review
  6. Impact ofInternational journal of molecular sciences · 2025
    Article
  7. Co-Infection Dynamics ofInternational journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yenesew Mihret WondmagegnDepartment of Medical Parasitology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia. yenesewmihiret@gmail.com.
Getu GirmayDepartment of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Gashaw Azanaw AmareDepartment of Medical Laboratory Sciences, Debre Markos University, Debre Markos, Ethiopia.
Muluneh AssefaDepartments of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Mebratu TamirDepartment of Medical Parasitology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Zufan Yiheyis AbrihamDepartment of Medical Parasitology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Abebaw SetegnDepartment of Medical Parasitology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal infections caused by intestinal parasites and Helicobacter pylori are significant public health issues in Africa, where poor sanitation and limited access to healthcare contribute to high disease burden. Since there was no previous pooled data regarding the intestinal parasites and Helicobacter pylori co-infections among gastrointestinal symptomatic patients in the African context, this review aimed to determine the overall prevalence of intestinal parasites and Helicobacter pylori co-infection in people with gastrointestinal symptoms in Africa.

methodsThe current review followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) standards and registered in the International Prospective Register of Systematic Reviews (PROSPERO; CRD42024598993). A comprehensive search was conducted across electronic databases: PubMed, Medline, EMBASE, Google Scholar, Web of Science, Science Direct, and African Journals Online. The data was extracted using Microsoft Excel 2010 and analyzed using STATA version 11.0 Software. A random-effects model was used to calculate the pooled effect size of outcome variables across studies, with a 95% confidence interval. The I

resultsThe combined prevalence of intestinal parasites and H. pylori co-infections was 31.03% (95% CI: 18.66-43.39) with significant heterogeneity (I

conclusionThis meta-analysis shows a significant prevalence of intestinal parasites and H. pylori co-infection in Africans with gastrointestinal symptoms. The coexistence of these diseases creates diagnostic and therapeutic problems. Thus, the findings underscore need for targeted interventions and further research is needed to develop effective control strategies to reduce the impact of these illnesses on public health in Africa.

Indexed as

CoinfectionHelicobacter InfectionsHelicobacter pyloriIntestinal Diseases, ParasiticAfricaHumansPrevalenceAfricaCo-infectionH. PyloriIntestinal parasites

Identifiers

PMID39754070
PMCPMC11699658

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.