Evidence map›Paper›PMID 39755741›Full record

ArticleScientific reports2025

Prevalence of anhedonia in women with deep endometriosis.

Aida Mallorquí, Alessandra Fortuna, Emma Segura, Gemma Cardona, Marta Espinosa, Lara Quintas-Marquès, Meritxell Gracia, Elena Angulo-Antúnez, Francisco Carmona, María-Angeles Martínez-Zamora

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aida MallorquíClinical Health Psychology Section, Institute of Neuroscience (ICN), Hospital Clinic, 08036, Barcelona, Spain.
Alessandra FortunaGynecology Department Institute Clinic of Gynecology, Obstetrics and Neonatology, Hospital Clinic, Faculty of Medicine, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, 08036, Barcelona, Spain.
Emma SeguraCognition and Brain Plasticity Unit, Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, 08907, Barcelona, Spain.
Gemma CardonaCognition and Brain Plasticity Unit, Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, 08907, Barcelona, Spain.
Marta EspinosaClinical Health Psychology Section, Institute of Neuroscience (ICN), Hospital Clinic, 08036, Barcelona, Spain.
Lara Quintas-MarquèsGynecology Department Institute Clinic of Gynecology, Obstetrics and Neonatology, Hospital Clinic, Faculty of Medicine, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, 08036, Barcelona, Spain.
Meritxell GraciaGynecology Department Institute Clinic of Gynecology, Obstetrics and Neonatology, Hospital Clinic, Faculty of Medicine, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, 08036, Barcelona, Spain.
Elena Angulo-AntúnezClinical Health Psychology Section, Institute of Neuroscience (ICN), Hospital Clinic, 08036, Barcelona, Spain.
Francisco Carmona *Gynecology Department Institute Clinic of Gynecology, Obstetrics and Neonatology, Hospital Clinic, Faculty of Medicine, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, 08036, Barcelona, Spain.
María-Angeles Martínez-Zamora *Gynecology Department Institute Clinic of Gynecology, Obstetrics and Neonatology, Hospital Clinic, Faculty of Medicine, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, 08036, Barcelona, Spain. mazamora@clinic.cat.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anhedonia, characterized by diminished motivation and pleasure sensitivity, is increasingly recognized as prevalent among patients with chronic pain. Deep Endometriosis (DE), the most severe endophenotype of the disease, is commonly presented with chronic pelvic pain. This cross-sectional study reports, for the first time, the prevalence of anhedonia in a sample comprised by 212 premenopausal women with suspected DE referred to a tertiary hospital. Our findings show that 27,8% [95% CI 22.1, 26.5] of DE patients experience abnormal hedonic tone. Severity of DE pain-related symptoms significantly correlated with anhedonia, consistent with previous findings. Chronic pelvic pain emerged as a significant predictor of anhedonia (OR 1.5, 95% CI 1.0-1.22, p < 0.05) with the odds increasing to 2.28 [95% CI 1.12, 4.23] when pain was severe. The most affected areas in DE patients were interests, social interaction and food pleasure. The present results are representative of DE patients under multimodal treatment, limiting generalizability. Overall, our study highlights the impact of chronic pain on hedonic functioning in DE. Therapeutic approaches targeting hedonic capacity in DE patients are crucial for restoring health and well-being.

Indexed as

AnhedoniaChronic PainEndometriosisAdultCross-Sectional StudiesFemaleHumansMiddle AgedPelvic PainPrevalenceYoung AdultAnhedoniaChronic painChronic pelvic painDeep endometriosisEndometriosisInflammation

Identifiers

PMID39755741
PMCPMC11700138

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.