Evidence map›Paper›PMID 39756004›Full record

ArticleNeuromolecular medicine2025

Imagine, Discover, Inspire: Proceedings of the 4th International Conference of the Trisomy 21 Research Society.

Lisi Flores-Aguilar, Eric D Hamlett, Paula Araya, Eugenio Barone, Anita Bhattacharyya, Maria Carmona-Iragui, Li Chan, Brad Christian, Alberto C S Costa, Floriana Costanzo and 26 more

Abstract readConference Proceedings
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuromolecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Lisi Flores-Aguilar *Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA, USA.
Eric D Hamlett *Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, USA.
Paula ArayaDepartment of Pediatrics, Section of Developmental Pediatrics, Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Eugenio BaroneDepartment of Biochemical Sciences "A. Rossi-Fanelli, Sapienza University of Rome, Rome, Italy.
Anita BhattacharyyaWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Maria Carmona-IraguiMemory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Li ChanCentre for Endocrinology, William Harvey Research Institute, Queen Mary University of London, London, UK.
Brad ChristianDepartment of Medical Physics and Psychiatry, University of Wisconsin-Madison, Madison, WI, USA.
Alberto C S CostaDepartment of Psychiatry, Case Western Reserve University, Cleveland, OH, USA.
Floriana CostanzoChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Laura Del Hoyo SorianoMemory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Mara DierssenCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Evan E EichlerDepartment of Genome Sciences, School of Medicine, University of Washington, Seattle, WA, USA.
Elizabeth FisherDepartment of Neuromuscular Diseases, LonDownS: London Down Syndrome Consortium, Queen Square Institute of Neurology, University College London, London, UK.
Matthew GalbraithDepartment of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.
Sujay GhoshCytogenetics and Genomics and Down Syndrome Research Unit, Department of Zoology, University of Calcutta, Kolkata, India.
Sandra GimenezMultidisciplinary Sleep Unit, Respiratory Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Faycal GuedjSection On Prenatal Genomics and Fetal Therapy, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Sandra GuidiDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Maria Florencia IulitaMemory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
William MobleyDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Maria Chiara PelleriDepartment of Biomedical and Neuromotor Sciences, Physiology Building, University of Bologna, Bologna, Italy.
Marie-Claude PotierInstitut du Cerveau-Paris Brain Institute-ICM, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Assistance Publique-Hôpitaux de Paris, Hôpital de la Pitié Salpêtrière, Sorbonne Université, Paris, France.
Karen R RabinDivision of Pediatric Hematology-Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX, USA.
Angela RachubinskiDepartment of Pediatrics, Section of Developmental Pediatrics, Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Anne-Sophie RebillatInstitut Jérôme Lejeune, Paris, France.
Eric RubensteinDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Hannah SaternosDepartment of Neurosurgery, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Lorena SordoDepartment of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA, USA.
Andre StrydomDepartment of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Natalia Valle-TamayoMemory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Katherine A WaughDepartment of Pediatrics, Section of Developmental Pediatrics, Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Eugene YuThe Children's Guild Foundation Down Syndrome Research Program, Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Ella ZeldichDepartment of Anatomy and Neurobiology, Boston University, Boston, MA, USA.
Jorge BusciglioNeurobiology and Behavior School of Biological Sciences, University of California, Irvine, CA, USA.
Elizabeth HeadDepartment of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA, USA. heade@uci.edu.

Funding

T21RS Meeting June 2022 Long Beach, CaliforniaR13HD108965 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI HEAD, ELIZABETH · 2022 to 2022
$38k
National Institute of Child Health and Human Development R13HD108965NICHD NIH HHS R13 HD108965
6 · The paper itself

Abstract

Down syndrome (DS) or trisomy 21 (T21) is present in a significant number of children and adults around the world and is associated with cognitive and medical challenges. Through research, the T21 Research Society (T21RS), established in 2014, unites a worldwide community dedicated to understanding the impact of T21 on biological systems and improving the quality of life of people with DS across the lifespan. T21RS hosts an international conference every two years to support collaboration, dissemination, and information sharing for this goal. In 2022, T21RS hosted an international conference in Long Beach, California, from June 9 to 12. The conference, attended by 483 people including scientists, families, self-advocates, and industry representatives from 17 countries, was a dynamic and interactive meeting that shared discoveries from international research teams. This summary highlights the scientific discoveries shared at the 4th T21RS meeting with the Imagine, Discover, Inspire theme.

Indexed as

Down SyndromeAdultAnimalsBiomedical ResearchChildFemaleHumansQuality of LifeBiomarkersClinical researchConference proceedingsDown syndromeIntellectual disabilityPreclinical research

Identifiers

PMID39756004
PMCPMC11700910

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.