Evidence map›Paper›PMID 39756646›Full record

ArticleComparative biochemistry and physiology. Part B, Biochemistry & molecular biology

Bone dynamics in zebrafish on low- and high-frequency diets.

Kathryn Bisaha, Simon Bagatto, Rebekah Harden, Randi Depp, Rachel Olson, Qin Liu, Janna M Andronowski, Richard L Londraville

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathryn BisahaUniversity of Akron, Department of Biology, Akron, OH, USA.
Simon BagattoUniversity of Akron, Department of Biology, Akron, OH, USA.
Rebekah HardenUniversity of Akron, Department of Biology, Akron, OH, USA.
Randi DeppUniversity of Akron, Department of Biology, Akron, OH, USA.
Rachel OlsonUniversity of Akron, Department of Biology, Akron, OH, USA.
Qin LiuUniversity of Akron, Department of Biology, Akron, OH, USA.
Janna M AndronowskiClinical Anatomy, Faculty of Medicine, Memorial University, Newfoundland, Canada.
Richard L LondravilleUniversity of Akron, Department of Biology, Akron, OH, USA. Electronic address: londraville@uakron.edu.

Funding

Using Established Leptin Signaling Mutants to Study Cell Physiology and Bone Development in ZebrafishR15DK124790 · NIDDK · UNIVERSITY OF AKRON · PI LIU, QIN, LONDRAVILLE, RICHARD LYLE · 2021 to 2021
$444k
NIDDK NIH HHS R15 DK124790
6 · The paper itself

Abstract

Zebrafish (Danio rerio) were fed high and low-frequency diets over 40 days to assess the effect of diet on bone parameters. Fish fed 3×/day (High) were significantly greater in total weight and length vs. fish fed 2×/week (Low; <0.01). The High group had significantly higher vertebral bone density (p = 0.0009) and lower bone volume (p = 0.04) compared to the Low group. Scales from the Low group also had higher density of resorption lacunae in their scales (p = 0.02). We interpret these data to hypothesize that higher leptin titers associated with reduced calorie intake is generally catabolic to bone in zebrafish.

Indexed as

Bone and BonesDietZebrafishAnimal FeedAnimalsBone DensityLeptinLeptinBoneDanio reriomicroCTOsteoblastOsteoclastScale

Identifiers

PMID39756646
PMCPMC11871991

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.