Evidence map›Paper›PMID 39757782›Full record

ReviewCancer medicine2025

Diagnostic and Prognostic Significance of Exosomes and Their Components in Patients With Cancers.

Zinnat Ara Moni, Zahid Hasan, Md Shaheen Alam, Nitai Roy, Farhadul Islam

Abstract readReview
In one paragraph

Review in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zinnat Ara MoniDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi, Bangladesh.
Zahid HasanDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi, Bangladesh.
Md Shaheen AlamDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi, Bangladesh.
Nitai RoyDepartment of Biochemistry and Molecular Biology, Patuakhali Science and Technology University, Patuakhali, Bangladesh.ORCID https://orcid.org/0000-0002-8454-6128
Farhadul IslamDepartment of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi, Bangladesh.ORCID https://orcid.org/0000-0001-5262-4702

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer is the second leading cause of human mortality worldwide. Extracellular vesicles (EVs) from liquid biopsy samples are used in early cancer detection, characterization, and surveillance. Exosomes are a subset of EVs produced by all cells and present in all body fluids. They play an important role in the development of cancer because they are active transporters capable of carrying the contents of any type of cell. The objective of this review was to provide a brief overview of the clinical implication of exosomes or exosomal components in cancer diagnosis and prognosis.

methodsAn extensive review of the current literature of exosomes and their components in cancer diagnosis and prognosis were carried out in the current study.

resultsTumor cells release exosomes that contribute to the formation of the pre-metastatic microenvironment, angiogenesis, invasion, and treatment resistance. On the contrary, tumor cells release more exosomes than normal cells, and these tumor-specific exosomes can carry the genomic and proteomic signature contents of the tumor cells, which can act as tools for the diagnosis and prognosis of patients with cancers.

conclusionThis information may help clinicians to improve the management of cancer patients in clinical settings in the future.

Indexed as

Biomarkers, TumorExosomesNeoplasmsHumansLiquid BiopsyPrognosisTumor MicroenvironmentBiomarkers, Tumorcancer progressiondiagnosis markersexosomessurvival

Identifiers

PMID39757782
PMCPMC11702466

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.