ArticleJournal of orthodontic science2024
Influence of pH on the release of nickel ions from fixed orthodontic appliances in artificial saliva.
Article in Journal of orthodontic science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study was to make a laboratory assessment of pH influence on the kinetics of the release of nickel ions in artificial saliva. METHODS AND MATERIAL: In this study, 15 basic orthodontic appliances are immersed in 15 polyethylene tubes each containing 40 ml of artificial saliva. Tubes were divided into three sub-groups of 5 tubes depending on the pH: pH 5, pH 7 and pH 8. The release of nickel ions was measured using atomic absorption spectrometry in a sample of 5 ml of artificial saliva taken one hour, four hours and one hundred and sixty-eight hours after immersion in a water bath at 37°. STATISTICAL ANALYSIS USED: Significance threshold
resultsThe neutral pH causes a low release of nickel ions. The release kinetics of nickel ions is minimal for neutral pH, it increases when pH varies. After one hour of immersion, the nickel released did not reach the spectrometer quantification threshold as for neutral and acid pH. The alkaline pH causes an average release of nickel ions from the beginning without kinetic variation. As time passes (T3), the acidic pH causes more nickel ions release through a succession of oxidation-reduction reactions. After 168 hours, the average mass of nickel released is 0.30 µg for pH 7, 1.35 µg for pH 8 and up to 2.85 µg for pH 5.
conclusionsQuantities released did not reach nickel toxicity threshold in humans. Orthodontists must consider the potential risk of hypersensitivity due to nickel in fixed orthodontic appliances.
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