Evidence map›Paper›PMID 39759076›Full record

ArticleiScience2024

Optical coherence tomography angiography enables visualization of microvascular patterns in chronic venous insufficiency.

Giulia Rotunno, Julia Deinsberger, Kristen M Meiburger, Lisa Krainz, Lukasz Bugyi, Valentin Hacker, Richard Haindl, Rainer Leitgeb, Christoph Sinz, Leopold Schmetterer and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Giulia RotunnoPolitoBIOMed Lab, Department of Electronics and Telecommunications, Politecnico di Torino, Torino, Italy.
Julia DeinsbergerDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Kristen M MeiburgerPolitoBIOMed Lab, Department of Electronics and Telecommunications, Politecnico di Torino, Torino, Italy.
Lisa KrainzCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Lukasz BugyiCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Valentin HackerDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Richard HaindlCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Rainer LeitgebCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Christoph SinzDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Leopold SchmettererCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Wolfgang DrexlerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Benedikt WeberDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Mengyang LiuCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic venous insufficiency (CVI) is a global health concern with significant public health and individual impact. Currently available diagnostic methods cannot visualize microvenous pathologies that have shown to result in severe forms of CVI and also affect the skin. Optical coherence tomography angiography (OCTA) may close the CVI diagnostic gap by providing a fast, label-free, and non-invasive solution to visualize cutaneous microvasculature. The study enlisted 66 subjects, including 53 CVI patients spanning all clinical-etiology-anatomic-pathophysiologic (CEAP) C stages and 13 healthy controls. The high spatial resolution OCTA system used was specifically designed for skin imaging. Significant microangiographic pattern variations emerged, both in qualitative and quantitative terms. OCTA provided valuable insights into cutaneous microvascular changes among different CVI stages. Thereby, OCTA may enable the selection of patient populations at risk for disease progression in the future.

Indexed as

Health sciencesOptical imagingVascular anatomy

Identifiers

PMID39759076
PMCPMC11700630

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.