ArticleHeliyon2024
Propolis does not significantly modulate immune function in an older population: A preliminary study.
Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The human trial aimed to study the influence of propolis on immune function in the elderly. Methods: Non-institutionalized community-dwelling individuals aged 60-80 years were recruited from Tianjin, China. Participants were assigned randomly to either the Chinese propolis group (600 mg/day, n = 32) or the control group (n = 30). Serum antibodies and biochemical indices were measured using commercial kits; cytokines were detected using ELISA assay, and the functions of lymphocytes and neutrophils were assayed using the MTT and Results: The study lasted for 12 weeks. Immunoglobulin G (IgG) levels notably increased at week 6 although these levels returned to baseline by week 12 in the Chinese propolis group. No significant difference was detected in serum antibodies, cytokines, or lymphocyte and neutrophil functions between the two groups at any time point. Conclusions: Chinese propolis could stimulate IgG secretion within a certain period, but it was restored to baseline levels over time. Propolis does not significantly affect other immune markers in the elderly.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.