Evidence map›Paper›PMID 39760004›Full record

Review3 Biotech2025

Nanoformulated phytochemicals in skin anti-aging research: an updated mini review.

Andrea G Uriostegui-Pena, Andrea Torres-Copado, Adriana Ochoa-Sanchez, Gabriel Luna-Bárcenas, Padmavati Sahare, Sujay Paul

Abstract readReview
In one paragraph

Review in 3 Biotech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea G Uriostegui-Pena *School of Engineering and Sciences, Tecnologico de Monterrey, Campus Querétaro, Av. Epigmenio Gonzalez, No. 500 Fracc. San Pablo, 76130 Querétaro, Mexico.
Andrea Torres-Copado *School of Engineering and Sciences, Tecnologico de Monterrey, Campus Querétaro, Av. Epigmenio Gonzalez, No. 500 Fracc. San Pablo, 76130 Querétaro, Mexico.
Adriana Ochoa-SanchezSchool of Engineering and Sciences, Tecnologico de Monterrey, Campus Querétaro, Av. Epigmenio Gonzalez, No. 500 Fracc. San Pablo, 76130 Querétaro, Mexico.
Gabriel Luna-BárcenasInstitute of Advanced Materials for Sustainable Manufacturing, Tecnologico de Monterrey, Campus Querétaro, Av. Epigmenio Gonzalez, No. 500 Fracc. San Pablo, 76130 Querétaro, Mexico.
Padmavati SahareInstitute of Advanced Materials for Sustainable Manufacturing, Tecnologico de Monterrey, Campus Querétaro, Av. Epigmenio Gonzalez, No. 500 Fracc. San Pablo, 76130 Querétaro, Mexico.
Sujay PaulSchool of Engineering and Sciences, Tecnologico de Monterrey, Campus Querétaro, Av. Epigmenio Gonzalez, No. 500 Fracc. San Pablo, 76130 Querétaro, Mexico.ORCID 0000-0001-5024-7261

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin aging is characterized by progressive loss of functionality and regenerative potential of the skin, resulting in the appearance of wrinkles, irregular pigmentation, a decrease of elasticity, dryness, and rough texture. Damage to the skin caused by oxidative stress could substantially be slowed down by the use of phytochemicals that function as natural antioxidants. Although phytochemicals have immense potential as anti-aging medicines, their effectiveness as therapeutic agents is restricted by their poor solubility, biodistribution, stability, and hydrophilicity. Given their improved stability, solubility, efficacy, and occlusive properties, nanoformulations have emerged as promising drug delivery platforms for phytochemicals to achieve anti-aging effects. The efficacy of these nanoformulated phytochemicals in suppressing enzymes that accelerate skin aging, such as collagenase, tyrosinase and hyaluronidase, as well as enhancing superoxide dismutase, catalase, and collagen levels to improve skin appearance during aging has been demonstrated.

Indexed as

Anti-aging propertyAntioxidantNanoformulationsPhytochemicalsSkinTherapeutics

Identifiers

PMID39760004
PMCPMC11699038

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.