Evidence map›Paper›PMID 39762049›Full record

ArticleGenome research2025

Ultraviolet damage and repair maps in

Benjamin Morledge-Hampton, Kathiresan Selvam, Manish Chauhan, Alan G Goodman, John J Wyrick

Abstract read
In one paragraph

Article in Genome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Illuminating genome repair by photolyase.Photochemistry and photobiology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin Morledge-Hampton *School of Molecular Biosciences, Washington State University, Pullman, Washington 99164, USA.
Kathiresan Selvam *School of Molecular Biosciences, Washington State University, Pullman, Washington 99164, USA.
Manish ChauhanSchool of Molecular Biosciences, Washington State University, Pullman, Washington 99164, USA.
Alan G GoodmanSchool of Molecular Biosciences, Washington State University, Pullman, Washington 99164, USA.ORCID 0000-0001-6394-332X
John J WyrickSchool of Molecular Biosciences, Washington State University, Pullman, Washington 99164, USA; jwyrick@wsu.edu.ORCID 0000-0002-7911-3803

Funding

Genome-wide analysis of the formation and mutagenesis of atypical UV photoproducts in skin cancerR01ES032814 · NIEHS · WASHINGTON STATE UNIVERSITY · PI STEVEN A ROBERTS, John J Wyrick · 2021 to 2026
$5.8M
Regulation of DNA Excision Repair in ChromatinR01ES028698 · NIEHS · WASHINGTON STATE UNIVERSITY · PI John J Wyrick · 2018 to 2026
$2.7M
The role of Elf1 in transcription coupled-nucleotide excision repairR21ES035888 · NIEHS · WASHINGTON STATE UNIVERSITY · PI SELVAM, KATHIRESAN, WYRICK, JOHN J · 2024 to 2025
$438k
NIEHS NIH HHS R01 ES028698NIEHS NIH HHS R01 ES032814NIEHS NIH HHS R21 ES035888
6 · The paper itself

Abstract

Cyclobutane pyrimidine dimers (CPDs) are formed in DNA following exposure to ultraviolet (UV) light and are mutagenic unless repaired by nucleotide excision repair (NER). It is known that CPD repair rates vary in different genome regions owing to transcription-coupled NER and differences in chromatin accessibility; however, the impact of regional chromatin organization on CPD formation remains unclear. Furthermore, nucleosomes are known to modulate UV damage and repair activity, but how these damage and repair patterns are affected by the overarching chromatin domains in which these nucleosomes are located is not understood. Here, we generated a new CPD damage map in

Indexed as

DNA DamageDNA RepairDrosophilaNucleosomesUltraviolet RaysAnimalsCell LineChromatinDrosophila melanogasterPyrimidine DimersChromatinNucleosomesPyrimidine Dimers

Identifiers

PMID39762049
PMCPMC11874968

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.