Evidence map›Paper›PMID 39762424›Full record

ArticleNature medicine2025

Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries.

Laura Lara-Castor, Meghan O'Hearn, Frederick Cudhea, Victoria Miller, Peilin Shi, Jianyi Zhang, Julia R Sharib, Sean B Cash, Simon Barquera, Renata Micha and 2 more

Erratum issuedAbstract read
In one paragraph

Article in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Steviol Glycosides (E960) FromFood science & nutrition · 2026
    Review
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  12. Article
  13. Observational
  14. Review
  15. Article
  16. Neural embedding of frailty in cognitively unimpaired aging and dementia across Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Laura Lara-CastorFood Is Medicine Institute, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA. lauralac@uw.edu.ORCID http://orcid.org/0000-0002-1750-5406
Meghan O'HearnFood Is Medicine Institute, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Frederick CudheaFood Is Medicine Institute, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Victoria MillerFood Is Medicine Institute, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0509-1549
Peilin ShiFood Is Medicine Institute, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Jianyi ZhangCenter for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, USA.
Julia R SharibFood Is Medicine Institute, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Sean B CashFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Simon BarqueraResearch Center on Nutrition and Health, National Institute of Public Health, Cuernavaca, Mexico.
Renata MichaFood Is Medicine Institute, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Dariush MozaffarianFood Is Medicine Institute, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA. dariush.mozaffarian@tufts.edu.ORCID http://orcid.org/0000-0001-7958-9492
Global Dietary Database

Funding

American Heart Association (American Heart Association, Inc.) 903679Bill and Melinda Gates Foundation (Bill & Melinda Gates Foundation) OPP1176682
6 · The paper itself

Abstract

The consumption of sugar-sweetened beverages (SSBs) is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). However, an updated and comprehensive assessment of the global burden attributable to SSBs remains scarce. Here we estimated SSB-attributable T2D and CVD burdens across 184 countries in 1990 and 2020 globally, regionally and nationally, incorporating data from the Global Dietary Database, jointly stratified by age, sex, educational attainment and urbanicity. In 2020, 2.2 million (95% uncertainty interval 2.0-2.3) new T2D cases and 1.2 million (95% uncertainty interval 1.1-1.3) new CVD cases were attributable to SSBs worldwide, representing 9.8% and 3.1%, respectively, of all incident cases. Globally, proportional SSB-attributable burdens were higher among men versus women, younger versus older adults, higher- versus lower-educated adults, and adults in urban versus rural areas. By world region, the highest SSB-attributable percentage burdens were in Latin America and the Caribbean (T2D: 24.4%; CVD: 11.3%) and sub-Saharan Africa (T2D: 21.5%; CVD: 10.5%). From 1990 to 2020, the largest proportional increases in SSB-attributable incident T2D and CVD cases were in sub-Saharan Africa (+8.8% and +4.4%, respectively). Our study highlights the countries and subpopulations most affected by cardiometabolic disease associated with SSB consumption, assisting in shaping effective policies and interventions to reduce these burdens globally.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Sugar-Sweetened BeveragesAdultAgedFemaleGlobal HealthHumansMaleMiddle Aged

Identifiers

PMID39762424
PMCPMC11835746

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.