Evidence mapPaperPMID 39762599Full record

ArticleJournal of patient-reported outcomes2025

Clinically meaningful classes of financial toxicity for patients with diabetes.

Minal R Patel, Jonathan P Troost, Michele Heisler, Noelle E Carlozzi

Abstract read
In one paragraph

Article in Journal of patient-reported outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Minal R PatelDepartment of Health Behavior and Health Equity, University of Michigan, 1415 Washington Heights, SPH 1, Room 3810, Ann Arbor, MI, 48109, USA. minalrp@umich.edu.ORCID http://orcid.org/0000-0002-3400-5155
Jonathan P TroostMichigan Institute for Clinical Health Research, University of Michigan, 1600 Huron Pkwy, Ann Arbor, MI, 48105, USA.
Michele HeislerDepartment of Health Behavior and Health Equity, University of Michigan, 1415 Washington Heights, SPH 1, Room 3810, Ann Arbor, MI, 48109, USA.
Noelle E CarlozziDepartment of Physical Medicine and Rehabilitation, University of Michigan, 1540 E. Hospital Dr, Ann Arbor, MI, 48109, USA.

Funding

Michigan Institute for Clinical and Health Research (MICHR)UM1TR004404 · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2025 to 2025
$9.8M
Pilot and Feasibility ProgramP30DK092926 · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2025 to 2025
$779k
NCATS NIH HHS UM1 TR004404NIDDK NIH HHS P30 DK092926NIDDK NIH HHS P30DK092926NIDDK NIH HHS R01 DK116715-01A1
6 · The paper itself

Abstract

aimsThis study aims to improve the interpretability and clinical utility of the COmprehensive Score for financial Toxicity-Functional Assessment of Chronic Illness Therapy (COST-FACIT) by identifying distinct financial toxicity classes in adults with diabetes.

methodsData included a sample of 600 adults with Type 1 or Type 2 diabetes and high A1c. Latent Class Analysis was used to identify subgroups of patients based on COST-FACIT score patterns.

resultsWe identified 3 financial toxicity classes (high, medium and low) with strong indicators of membership classification. Multiple indicators of financial stress, maladaptive cost-coping behaviors, more comorbidities, more prescribed medications, more diabetes distress, more depressive symptoms, closer to the federal poverty level, female, having lower educational attainment and being single were all significant predictors of high financial toxicity class membership. A score of 26 on the COST-FACIT was the strongest threshold for sorting high vs. medium/low financial toxicity, with a positive predictive value (PPV) of 76% and negative predictive value (NPV) of 93%.

conclusionThe COST-FACIT can be used to reliably identify people with diabetes that have high financial toxicity. Integrating this new cut-score into clinical practice may help clinical teams identify people in need of additional support due to financial toxicity.

Indexed as

Diabetes Mellitus, Type 2Financial StressAdaptation, PsychologicalAdultAgedCost of IllnessDiabetes Mellitus, Type 1FemaleHumansLatent Class AnalysisMaleMiddle AgedClinical practiceDiabetesFinancial burdenFinancial toxicity

Identifiers

PMID39762599
PMCPMC11704103

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.