Evidence map›Paper›PMID 39763850›Full record

ArticlebioRxiv : the preprint server for biology2024

Interleukin-1β Drives Disease Progression in Arrhythmogenic Cardiomyopathy.

Vinay R Penna, Junedh M Amrute, Morgan Engel, Emily A Shiel, Waleed Farra, Elisa N Cannon, Colleen Leu-Turner, Pan Ma, Ana Villanueva, Haewon Shin and 7 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Vinay R PennaCenter for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine; St. Louis, MO, USA.ORCID 0000-0002-9082-7874
Junedh M AmruteCenter for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine; St. Louis, MO, USA.ORCID 0000-0002-6851-0168
Morgan EngelDepartment of Biomedical Sciences, Florida State University College of Medicine; Tallahassee, FL, USA.
Emily A ShielDepartment of Biomedical Sciences, Florida State University College of Medicine; Tallahassee, FL, USA.ORCID 0009-0009-6491-4331
Waleed FarraDepartment of Biomedical Sciences, Florida State University College of Medicine; Tallahassee, FL, USA.
Elisa N CannonDepartment of Biomedical Sciences, Florida State University College of Medicine; Tallahassee, FL, USA.
Colleen Leu-TurnerDepartment of Biomedical Sciences, Florida State University College of Medicine; Tallahassee, FL, USA.ORCID 0000-0003-3181-9345
Pan MaCenter for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine; St. Louis, MO, USA.
Ana VillanuevaDepartment of Pathology and Immunology, Washington University in St. Louis School of Medicine; St. Louis, MO, USA.ORCID 0000-0002-6637-3745
Haewon ShinCenter for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine; St. Louis, MO, USA.ORCID 0000-0001-6316-8474
Alekhya ParvathaneniCenter for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine; St. Louis, MO, USA.ORCID 0000-0002-2976-1941
Joanna JagerCardiovascular and Genomics Research Institute, School of Health & Medical Sciences, City St George's, University of London.
Carlos Bueno-BetiCardiovascular and Genomics Research Institute, School of Health & Medical Sciences, City St George's, University of London.ORCID 0000-0003-4626-1276
Angeliki AsimakiCardiovascular and Genomics Research Institute, School of Health & Medical Sciences, City St George's, University of London.ORCID 0000-0001-9886-6870
Kory J LavineCenter for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University in St. Louis School of Medicine; St. Louis, MO, USA.ORCID 0000-0003-1948-9945
Jeffrey E SaffitzDepartment of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School; Boston, MA, USA.ORCID 0000-0001-8568-9457
Stephen P ChelkoDepartment of Biomedical Sciences, Florida State University College of Medicine; Tallahassee, FL, USA.ORCID 0000-0003-1675-5945

Funding

TRAINING PROGRAM IN IMMUNOLOGY AND IMMUNOGENETICST32AI007163 · NIAID · WASHINGTON UNIVERSITY · PI Kenneth M Murphy, Kodi S Ravichandran · 1985 to 2026
$14.8M
Washington University Rheumatic DiseasesResearch Resource-based CenterP30AR073752 · NIAMS · WASHINGTON UNIVERSITY · PI LENSCHOW, DEBORAH J, PHAM, CHRISTINE T. · 2018 to 2025
$6.1M
Specification and Function of Tissue Resident and Recruited Macrophages in Cardiac Remodeling and Heart FailureR35HL161185 · NHLBI · WASHINGTON UNIVERSITY · PI Kory J. Lavine · 2022 to 2026
$4.3M
Arrhythmogenic Cardiomyopathy is an Inflammatory DiseaseR01HL148348 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SAFFITZ, JEFFREY E · 2020 to 2023
$2.1M
British Heart Foundation PG/23/11166NHLBI NIH HHS R01 HL148348NHLBI NIH HHS R35 HL161185NIAID NIH HHS T32 AI007163NIAMS NIH HHS P30 AR073752
6 · The paper itself

Abstract

Arrhythmogenic cardiomyopathy (ACM) is a genetic form of heart failure that affects 1 in 5000 people globally and is caused by mutations in cardiac desmosomal proteins including

Identifiers

PMID39763850
PMCPMC11702578

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.