Evidence map›Paper›PMID 39763862›Full record

ArticlebioRxiv : the preprint server for biology2024

Sexually dimorphic ATF4 expression in the fat confers female stress tolerance in

Lydia Grmai, Melissa Mychalczuk, Aditya Arkalgud, Deepika Vasudevan

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Lydia GrmaiDepartment of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0001-5465-7401
Melissa MychalczukDepartment of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Aditya ArkalgudDepartment of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Deepika VasudevanDepartment of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0003-1930-3549

Funding

Digestive Diseases Training ProgramT32DK063922 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ARTEEL, GAVIN E, YADAV, DHIRAJ · 2003 to 2022
$5.2M
Elucidating the role of the Integrated Stress Response pathway in tissue homeostasis - Admin SupplementR35GM150516 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Deepika Vasudevan · 2023 to 2026
$1.7M
ER stress-induced translational regulation in retinal degenerationR00EY029013 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VASUDEVAN, DEEPIKA · 2021 to 2023
$724k
Stress response signaling as a metabolic sensor in reproductionK99GM149982 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GRMAI, LYDIA · 2023 to 2024
$198k
NEI NIH HHS R00 EY029013NIDDK NIH HHS T32 DK063922NIGMS NIH HHS K99 GM149982NIGMS NIH HHS R35 GM150516
6 · The paper itself

Abstract

Metabolic differences between males and females have been well documented across many species. However, the molecular basis of these differences and how they impact tolerance to nutrient deprivation is still under investigation. In this work, we use

Indexed as

adiposeATF4dimorphismdoublesexmethioninasesplicingstresstransformer

Identifiers

PMID39763862
PMCPMC11703189

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.