Evidence map›Paper›PMID 39763942›Full record

ArticlebioRxiv : the preprint server for biology2024

Cell cycle-regulated transcriptional pausing of

James P Kemp, Mark S Geisler, Mia Hoover, Chun-Yi Cho, Patrick H O'Farrell, William F Marzluff, Robert J Duronio

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

James P KempIntegrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, NC, 27599 USA.ORCID 0000-0003-1975-1149
Mark S GeislerCurriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC, 27599 USA.ORCID 0000-0002-2900-4609
Mia HooverDepartment of Biology, University of North Carolina, Chapel Hill, NC, 27599 USA.
Chun-Yi ChoDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158.
Patrick H O'FarrellDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158.
William F MarzluffIntegrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, NC, 27599 USA.
Robert J DuronioIntegrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, NC, 27599 USA.

Funding

HISTONE MRNA REGULATION IN DEVELOPMENTR01GM058921 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DURONIO, ROBERT J, MARZLUFF, WILLIAM F. · 1999 to 2025
$11.6M
Embryonic Emergence of Heterochromatin and Nuclear Supervision of Mitochondrial GeneticsR35GM136324 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI O'FARRELL, PATRICK H · 2020 to 2024
$4.1M
Epigenetic Control of the Cell Cycle During Animal DevelopmentR35GM145258 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Robert J Duronio · 2022 to 2026
$2.3M
The Mute button: Turning down the volume of histone expressionF31HD113267 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GEISLER, MARK STEPHEN · 2023 to 2025
$146k
NICHD NIH HHS F31 HD113267NIGMS NIH HHS R01 GM058921NIGMS NIH HHS R35 GM136324NIGMS NIH HHS R35 GM145258
6 · The paper itself

Abstract

Coordinated expression of replication-dependent (RD) histones genes occurs within the Histone Locus Body (HLB) during S phase, but the molecular steps in transcription that are cell cycle regulated are unknown. We report that

Indexed as

biomolecular condensatescell cycleDrosophilahistonestranscription

Identifiers

PMID39763942
PMCPMC11702538

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.