Evidence map›Paper›PMID 39763953›Full record

ArticlebioRxiv : the preprint server for biology2024

SLC35A2 loss of function variants affect glycomic signatures, neuronal fate, and network dynamics.

Dulcie Lai, Paulina Sosicka, Damian J Williams, MaryAnn E Bowyer, Andrew K Ressler, Sarah E Kohrt, Savannah J Muron, Peter B Crino, Hudson H Freeze, Michael J Boland and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Dulcie LaiDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.
Paulina SosickaHuman Genetics Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, 92037, USA.
Damian J WilliamsInstitute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA.
MaryAnn E BowyerDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.
Andrew K ResslerInstitute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Sarah E KohrtDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.
Savannah J MuronDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.
Peter B CrinoDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Hudson H FreezeHuman Genetics Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, 92037, USA.
Michael J BolandInstitute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Erin L HeinzenDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
UNC Neuroscience Center Research Cores: MicroscopyP30NS045892 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZYLKA, MARK J. · 2003 to 2022
$11.5M
Preclinical CoreP50HD103573 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Mark D Shen · 2020 to 2026
$9.7M
Identification and molecular characterization of somatic mutations in MCDR01NS094596 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Peter B Crino, Erin L HEINZEN · 2016 to 2026
$5.9M
Defining disease mechanisms in SLC35A2 epilepsyR01NS115017 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CRINO, PETER B, HEINZEN, ERIN L · 2020 to 2024
$3.7M
NCATS NIH HHS UL1 TR001873NICHD NIH HHS P50 HD103573NINDS NIH HHS P30 NS045892NINDS NIH HHS R01 NS094596NINDS NIH HHS R01 NS115017
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

epilepsyglycosylationhuman stem cellsneural networkneurodevelopment

Identifiers

PMID39763953
PMCPMC11703275

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.