Evidence map›Paper›PMID 39764154›Full record

ReviewNon-coding RNA research2024

Exploring the role of noncoding RNAs in cancer diagnosis, prognosis, and precision medicine.

Basmah Eldakhakhny, Abdulaziz M Sutaih, Moaaz A Siddiqui, Yamin M Aqeeli, Akram Z Awan, Mohammad Y Alsayegh, Salma A Elsamanoudy, Ayman Elsamanoudy

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Non-coding RNA research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Non-coding RNA profiling in BRAFScientific data · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Basmah EldakhakhnyClinical Biochemistry Department, Faculty of Medicine, King Abdulaziz University, Jeddah, 21465, Saudi Arabia.
Abdulaziz M SutaihFaculty of Medicine, King Abdulaziz University, Jeddah, 21465, Saudi Arabia.
Moaaz A SiddiquiFaculty of Medicine, King Abdulaziz University, Jeddah, 21465, Saudi Arabia.
Yamin M AqeeliFaculty of Medicine, King Abdulaziz University, Jeddah, 21465, Saudi Arabia.
Akram Z AwanFaculty of Medicine, King Abdulaziz University, Jeddah, 21465, Saudi Arabia.
Mohammad Y AlsayeghFaculty of Medicine, King Abdulaziz University, Jeddah, 21465, Saudi Arabia.
Salma A ElsamanoudyMansoura-Manchester Medical Program for Medical Education, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt.
Ayman ElsamanoudyClinical Biochemistry Department, Faculty of Medicine, King Abdulaziz University, Jeddah, 21465, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review article studies the complex field of noncoding RNAs (ncRNAs) in cancer biology, focusing on their potential use as biomarkers and therapeutic targets. NcRNAs include circular RNAs (circRNAs), long noncoding RNAs (lncRNAs), and microRNAs (miRNAs). We discuss how ncRNAs affect gene expression in cancerous cells, the spread of cancer, and metastasis. The article illustrates the complex pathways through which ncRNAs can affect oncogenesis, tumor suppression, and therapeutic resistance. It also assesses the potential clinical uses of non-coding RNAs (ncRNAs), including their utility in cancer diagnosis, and prognosis. Besides, their potential for personalized cancer therapy is documented. Finally, it is concluded that understanding the role of ncRNA is of clinical importance regarding carcinogenesis, cancer diagnosis, and personalized therapy.

Indexed as

BiomarkersCancer biologyCircular RNAs (circRNAs)DiagnosisLong noncoding RNAs (lncRNAs)MicroRNAs (miRNAs)Noncoding RNAs (ncRNAs)Personalized medicinePrognosis

Identifiers

PMID39764154
PMCPMC11703603

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.