Evidence map›Paper›PMID 39764419›Full record

ReviewExploration of targeted anti-tumor therapy2024

Nigerian medicinal plants with potential anticancer activity-a review.

Mansurah A Abdulazeez, Hiba A Jasim, Temidayo D Popoola, Saheed O Benson, Jiradej Manosroi, Abdullahi B Sallau, Musa A Tabari, Amos A Fatokun

Abstract readReview
In one paragraph

Review in Exploration of targeted anti-tumor therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mansurah A AbdulazeezCenter for Biotechnology Research, Bayero University, Kano, Kano State, Nigeria.ORCID https://orcid.org/0000-0002-2233-1324
Hiba A JasimDepartment of Biology, College of Education for Pure Sciences, University of Anbar, Ramadi, Iraq.ORCID https://orcid.org/0000-0002-3637-3090
Temidayo D PopoolaCenter for Natural Products Discovery (CNPD), School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK.ORCID https://orcid.org/0000-0001-8503-2500
Saheed O BensonCenter for Natural Products Discovery (CNPD), School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK.ORCID https://orcid.org/0009-0008-6095-1779
Jiradej ManosroiDepartment of Cosmetic Technology, Faculty of Engineering, North-Chiang Mai University, Chiang Mai, Thailand.ORCID https://orcid.org/0000-0003-0384-9467
Abdullahi B SallauDepartment of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria.ORCID https://orcid.org/0000-0003-3715-8656
Musa A TabariDepartment of Radiology, Barau Dikko Teaching Hospital (BDTH), Kaduna State University (KASU), Kaduna, Nigeria.
Amos A FatokunCenter for Natural Products Discovery (CNPD), School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK.ORCID https://orcid.org/0000-0001-5183-7589

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the fact that life expectancies are increasing and the burden of infectious diseases is decreasing, global cancer incidence rates are on the rise. Cancer outcome metrics are dismal for low- and middle-income countries (LMICs), including sub-Saharan Africa, where adequate resources and infrastructure for cancer care and control are lacking. Nigeria, the most populous country in Africa, exemplifies the miserable situation. However, the investigation of medicinal plants for better and safer anti-cancer drugs has now increased tremendously. While scientific evidence is emerging of the potential of some constituents of medicinal plants used in traditional medicine in Nigeria to have anti-cancer effects, there is now a critical need for platforms that integrate ethnomedicinal information on such plants with emerging scientific data on them, to support and accelerate the discovery and development of more efficacious and safer anti-cancer drugs and recipes. Thus, this review highlights the scientific evidence to date for the anti-cancer potential of plants commonly used in traditional medicine to treat cancers in Nigeria. Scientific databases such as PubMed, Science Direct, Scopus, Google Scholar, and Web of Science, as well as related sources, were searched to retrieve relevant information on anti-cancer medicinal plants. Ethnobotanical/ethnomedicinal details of the identified plants were then linked with the available scientific data on their anti-cancer potential, including the cytotoxicity to cancer and normal cells of the extracts and constituent compounds responsible for the activity. This annotated chronicle of Nigerian medicinal plants with potential anticancer activity is a great resource for all stakeholders in the prevention and management of cancers.

Indexed as

Cancerchemotherapycytotoxicityethnomedicinemedicinal plantsNigeria

Identifiers

PMID39764419
PMCPMC11702266

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.