Evidence mapPaperPMID 39766340Full record

ArticleBiomolecules2024

The Influence of Bariatric Surgery on Matrix Metalloproteinase Plasma Levels in Patients with Type 2 Diabetes Mellitus.

João Kleber de Almeida Gentile, Renato Migliore, Jaques Waisberg, Marcelo Augusto Fontenelle Ribeiro Junior

Abstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

João Kleber de Almeida GentileDepartament of Surgery, Institute of Infectology Emilio Ribas (IIER), São Paulo 01246-900, SP, Brazil.ORCID 0000-0001-8650-2703
Renato MiglioreDepartment of Surgery, Hospital São Camilo, São Paulo 02401-200, SP, Brazil.
Jaques WaisbergDepartment of Surgery, ABC Medical School, Santo André 09060-870, SP, Brazil.ORCID 0000-0003-2775-8068
Marcelo Augusto Fontenelle Ribeiro JuniorDepartment of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD 21201, USA.ORCID 0000-0001-9826-4722

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBariatric surgery is a safe and effective procedure for treating obesity and metabolic conditions such as type 2

objectivesTo evaluate the effect of weight loss in bariatric surgery patients using oxidative stress markers and to compare MMP levels in patients undergoing bariatric surgery.

methodsThis was a prospective, controlled study including 45 morbidly obese patients with T2DM (BMI > 35 kg/m

resultsSignificant and sustained weight loss was observed after surgery in both groups, with reductions in BMI. MMP-2 and MMP-9 levels decreased significantly after one year of follow-up.

conclusionsBariatric surgery is an effective long-term intervention for weight loss and associated comorbidities, including T2DM. MMP-2 and MMP-9 proved to be effective markers of extracellular matrix remodeling, with significant reductions following surgery.

Indexed as

Bariatric SurgeryDiabetes Mellitus, Type 2Matrix Metalloproteinase 2Matrix Metalloproteinase 9AdultBiomarkersFemaleHumansMaleMiddle AgedObesity, MorbidProspective StudiesWeight LossBiomarkersMatrix Metalloproteinase 2Matrix Metalloproteinase 9MMP2 protein, humanMMP9 protein, humanbariatric surgerydiabetes mellitusgastric bypassgastroplastymatrix metalloproteinasesmorbid obesity

Identifiers

PMID39766340
PMCPMC11727344

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.