Evidence mapPaperPMID 39767130Full record

ArticleDiagnostics (Basel, Switzerland)2024

Genetic Associations of

Azhar Dyussupova, Gulnara Svyatova, Galina Berezina, Altay Dyussupov, Bauyrzhan Omarkulov, Anastassiya Dzharmukhametova, Oxana Yurkovskaya, Venera Akhmetova, Asylzhan Dyussupova

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Azhar DyussupovaDepartment of General Medical Practice, Semey Medical University, Semey 071400, Kazakhstan.
Gulnara SvyatovaLaboratory of Republican Medical Genetic Consultation, Scientific Center of Obstetrics, Gynecology and Perinatology, Almaty 050020, Kazakhstan.
Galina BerezinaLaboratory of Republican Medical Genetic Consultation, Scientific Center of Obstetrics, Gynecology and Perinatology, Almaty 050020, Kazakhstan.ORCID 0000-0002-5442-4461
Altay DyussupovDepartment of General Medical Practice, Semey Medical University, Semey 071400, Kazakhstan.
Bauyrzhan OmarkulovDepartment of Public Health and Occupational Health, NCJSC Medical University of Karaganda, Karaganda 100012, Kazakhstan.
Anastassiya DzharmukhametovaDepartment of General Medical Practice, Semey Medical University, Semey 071400, Kazakhstan.
Oxana YurkovskayaDepartment of General Medical Practice, Semey Medical University, Semey 071400, Kazakhstan.
Venera AkhmetovaDepartment of General Medical Practice, Semey Medical University, Semey 071400, Kazakhstan.
Asylzhan DyussupovaDepartment of General Medical Practice, Semey Medical University, Semey 071400, Kazakhstan.

Funding

Ministry of Science and Higher Education of the Republic of Kazakhstan AR 14870019
6 · The paper itself

Abstract

backgroundThis study aims to investigate the genetic contribution of polymorphic variants of the MATERIALS AND

methodsThis was a case-control study involving 200 cases with prediabetes and 200 prediabetes-free controls, aged 16-60 years (

resultsPatients with prediabetes had a higher birth weight, increased BMI, larger waist and hip circumferences, and a higher waist-to-hip ratio compared to healthy patients in the control group. There was a significant increase in the risk of developing prediabetes for both the

conclusionsThese findings highlight the need for tailored early screening and preventive strategies for prediabetes in the Kazakh population, focusing on individuals with high-risk genotypes. Such efforts could improve targeted interventions and reduce the burden of prediabetes. Future research should adopt a longitudinal design, include diverse ethnic groups, and investigate additional genetic markers to provide a more comprehensive understanding of the genetic underpinnings of prediabetes.

Indexed as

ethnic Kazakhsgenetic polymorphismsprediabetesrs1801282rs7903146

Identifiers

PMID39767130
PMCPMC11674111

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.