Evidence map›Paper›PMID 39767169›Full record

ArticleDiagnostics (Basel, Switzerland)2024

The Impact of Persevering Home Full-Body In-Bed Gym Exercise on Body Muscles in Aging: A Case Report by Quantitative Radio-Densitometric Study Using 3D and 2D Color CT.

Riccardo Forni, Paolo Gargiulo, Gabriele Boretti, Marco Quadrelli, Tommaso Baccaglini, Aldo Morra, Barbara Ravara, Sandra Zampieri, Amber Pond, Ugo Carraro and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Riccardo ForniInstitute of Biomedical and Neural Engineering, Reykjavik University, 101 Reykjavik, Iceland.
Paolo GargiuloInstitute of Biomedical and Neural Engineering, Reykjavik University, 101 Reykjavik, Iceland.
Gabriele BorettiInstitute of Biomedical and Neural Engineering, Reykjavik University, 101 Reykjavik, Iceland.ORCID 0009-0005-2276-0400
Marco QuadrelliSynlab Euganea Medica, 35020 Padua, Italy.ORCID 0000-0002-3811-7859
Tommaso BaccagliniSynlab Euganea Medica, 35020 Padua, Italy.ORCID 0009-0009-4491-4940
Aldo MorraSynlab Euganea Medica, 35020 Padua, Italy.ORCID 0000-0003-4378-5453
Barbara RavaraDepartment of Biomedical Sciences, University of Padova, 35131 Padua, Italy.
Sandra ZampieriDepartment of Biomedical Sciences, University of Padova, 35131 Padua, Italy.ORCID 0000-0001-6970-0011
Amber PondAnatomy Department, Southern Illinois University, Carbondale, IL 62901, USA.
Ugo CarraroDepartment of Biomedical Sciences, University of Padova, 35131 Padua, Italy.ORCID 0000-0002-0924-4998
Maria Chiara MaccaroneDepartment of Neuroscience, Section of Rehabilitation, University of Padova, 35128 Padua, Italy.ORCID 0000-0003-2793-1334
Stefano MasieroCIR-Myo-Interdepartmental Research Center of Myology, University of Padova, 35131 Padua, Italy.ORCID 0000-0002-0361-4898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Clinical Significance: Sarcopenia, characterized by muscle loss and fat infiltration, poses a significant health burden for aging populations. Quantitative Color 2D and 3D radiodensitometry provides a powerful tool to monitor muscle quality and quantity through CT imaging. This study assessed the impact of a ten-year-long home-bed gym exercise intervention on muscle quality in an elderly subject using CT-derived radiodensitometric analysis. The study involved two comparative analyses: Study A, which compared knee-to-ankle CT scans of the subject between 2013 and 2023; and Study B, which compared the subject's 2023 thigh CT scan with a cohort of 2500 elderly Icelandic individuals from the AGES-Reykjavik study. CASE PRESENTATION: A 70-year-old male began a home-based Full-Body In-Bed Gym exercise program in 2013. Quantitative muscle volume and radiodensity measurements were performed using CT at baseline and after ten years.

resultsStudy A shows significant improvements in muscle volume observed in the knee-to-ankle region, while a slower decline in radiodensity was noted, indicating substantial preservation of muscle quality despite the expected decay of ten-year aging. For instance, muscle volume increased by 15% in the left Soleus muscle and by 6% in the right Soleus muscle, while the average radiodensity decreased by 12-17 HU. The subject's thigh muscle quality at 80-years-old is above the AGES-Reykjavik's cohort average, with reduced fat infiltration.

conclusionsLong-term home Full-Body In-Bed Gym, a low-impact exercise, can mitigate aging sarcopenia, as evidenced by improved tissue radiodensity and muscle mass substantial preservation. This suggests potential applications in personalized healthcare strategies to enhance muscle preservation among aging populations.

Indexed as

agingcomputed tomographyhome Full-Body In-Bed exercisemuscle qualityradiodensitometrysarcopenia

Identifiers

PMID39767169
PMCPMC11674620

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.