ReviewChildren (Basel, Switzerland)2024
Myopia in Children: Epidemiology, Genetics, and Emerging Therapies for Treatment and Prevention.
Review in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exploring the efficacy of repeated low-level red-light therapy in retarding childhood myopia progression: updated systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Community-based paediatric eye care in low- and middle-income countries: bridging the gap between policy and practice.BMJ paediatrics open · 2026Review
- Modern Methods for Preventing the Progression of Myopia in Children.Journal of clinical medicine · 2026Review
- GPT-5-assisted versus expert surgeon refractive planning in smooth incision lenticule keratomileusis (SILK): comparative analysis and visual outcomes.International ophthalmology · 2026Observational
- Refractive status, visual behaviour, and parental myopia in Portuguese schoolchildren and adolescents.BMC pediatrics · 2026Article
- Lifestyle and environmental risk factors for myopia in children: Evidence from a large-scale cross-sectional study in Shandong, China.PloS one · 2026Article
- Atropine Eye Drops in Childhood Myopia Control: A Review.International journal of medical sciences · 2026Review
- Interventional modalities for the prevention and management of childhood myopia in frontiers in ophthalmology: PREC strategy for myopia in children.Frontiers in ophthalmology · 2026Article
- Symptoms of Depression and Anxiety among Myopes: A Systematic Review and Meta-Analysis.The British and Irish orthoptic journal · 2026Review
- Benchmark analysis of myopia-related issues using large language models: a comparison of ChatGPT-4o and deepseek.BMC ophthalmology · 2025Article
- Prediction of Myopia Among Undergraduate Students Using Ensemble Machine Learning Techniques.Health science reports · 2025Article
- Comparison of two main orthokeratology lens designs in effectiveness and safety for myopia control in different ages.Frontiers in medicine · 2025Article
- Sustainability in Cataract and Refractive Surgery: Current Challenges and Future Perspectives.Journal of ophthalmology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Refractive errors, particularly myopia, are among the most prevalent visual impairments globally, with rising incidence in children and adolescents. This review explores the epidemiology and risk factors associated with the development of refractive errors, focusing on the environmental and lifestyle factors contributing to the current surge in myopia. We provide an overview of key genetic factors and molecular pathways driving the pathogenesis of myopia and other refractive errors, emphasizing the complex interplay between genetic predisposition and environmental triggers. Understanding the underlying mechanisms is crucial for identifying new strategies for intervention. We discuss current approaches to slow myopia progression in pediatric populations, including pharmacological treatment regimens (low-dose atropine), optical interventions, and lifestyle modifications. In addition to established therapies, we highlight emerging innovations, including new pharmacological agents and advanced optical devices, and insights into potential future treatments. Cutting-edge research into gene therapy, molecular inhibitors, and neuroprotective strategies may yield novel therapeutic targets that address the root causes of refractive errors. This comprehensive review underscores the importance of early intervention and highlights promising avenues for future research, aiming to provide pediatricians with guidance to ultimately improve clinical outcomes in managing and preventing myopia progression in children and young adults.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.