ReviewLife (Basel, Switzerland)2024
Age and Sex Differences in Carotid Intima-Media Thickness: A Systematic Review and Meta-Analysis.
Review in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Associations of atherogenic index of plasma related indices with subclinical carotid atherosclerosis.Annals of medicine · 2026Article
- Preoperative carotid ultrasound in degenerative cervical myelopathy: from routine screening to selective use.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Low-frequency resistance training enhances 2D strain-derived carotid strain and strain rate: a novel longitudinal application of strain imaging in healthy middle-aged females.European journal of applied physiology · 2026Article
- Article
- Subclinical atherosclerosis in rheumatoid arthritis: a case cohort analysis from ELSA-Brasil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026Article
- Rotating shift work, with night shift work, affects cardiovascular risk factors: a 6-year follow-up study in the insulation industry.Occupational and environmental medicine · 2025Article
- Association of skin-advanced glycation end products, IMT complex, and bone mineral density in patients with type 1 diabetes.Frontiers in endocrinology · 2025Article
- The Effects of Smoking and Airway Restriction on Subclinical Atherosclerosis.International journal of chronic obstructive pulmonary disease · 2025Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundAgeing is a significant risk factor for carotid atherosclerosis, affecting over a billion people worldwide. Carotid intima-media thickness (cIMT) is a surrogate marker for cardiovascular disease (CVD) risk, with age- and sex-related differences in levels and progression. The onset of clinical manifestations of CVD in women is delayed by about 10 years compared to men. The present study aims to evaluate whether subclinical atherosclerosis is the same disease in men and women or two pathologies with a possible different etiology. For this purpose, we analyzed the differences in cIMT, the impact of patient characteristics, and the influence of age on cIMT in men and women.
methodsA systematic search related to cIMT measured by an ultrasound and gender-specific differences was conducted according to the PRISMA 2020 guidelines. Ninety studies, enrolling 165,551 subjects (76,955 men and 88,553 women), were included in the quantitative synthesis.
resultsWe found that men compared to women had greater common cIMT, (standardized mean difference (SMD) = 0.506,
conclusionsThis study showed that classical risk factors for CVD have a comparable effect on cIMT in men and women. While subclinical atherosclerotic disease, as assessed by cIMT, is essentially identical in the two sexes, it manifests itself by about 10 years later in women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.