Evidence mapPaperPMID 39769039Full record

ArticleInternational journal of molecular sciences2024

IL-6 Does Not Influence the Expression of

Maria Brodnanova, Michal Cibulka, Marian Grendar, Eduard Gondas, Martin Kolisek

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria BrodnanovaBiomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University Bratislava, 03601 Martin, Slovakia.ORCID 0000-0001-7350-1461
Michal CibulkaBiomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University Bratislava, 03601 Martin, Slovakia.ORCID 0000-0001-9245-9991
Marian GrendarBiomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University Bratislava, 03601 Martin, Slovakia.
Eduard GondasDepartment of Pharmacology, Jessenius Faculty of Medicine in Martin, Comenius University Bratislava, 03601 Martin, Slovakia.
Martin KolisekBiomedical Centre Martin, Jessenius Faculty of Medicine in Martin, Comenius University Bratislava, 03601 Martin, Slovakia.

Funding

Ministry of Education, Research, Development, and Youth of the Slovak Republic VEGA 1/0371/21Slovak Research and Development Agency APVV-19-0222
6 · The paper itself

Abstract

Together with chronic inflammation, disturbed magnesium homeostasis is a factor accompanying chronic disease which thus contributes to a reduced quality of human life. In this study, our objective was to examine the possible IL-6-mediated chronic inflammation-dependent regulation of nine magnesiotropic genes encoding for constituents of magnesium homeostasis of the cell. We used three cell lines (HepG2, U-266, and PANC-1), all characterized by high expression of the

Indexed as

Cation Transport ProteinsHomeostasisInterleukin-6MagnesiumCell Line, TumorGene Expression RegulationHep G2 CellsHumansReceptors, Interleukin-6Signal TransductionSTAT3 Transcription FactorCation Transport ProteinsInterleukin-6MagnesiumReceptors, Interleukin-6SLC41A1 protein, humanSTAT3 Transcription Factorinflammationinterleukin-6magnesiumSLC41A1STAT3

Identifiers

PMID39769039
PMCPMC11675721

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.