Evidence map›Paper›PMID 39769100›Full record

ArticleInternational journal of molecular sciences2024

Design, Synthesis, and Biological Evaluation of Novel Urea-Containing Carnosic Acid Derivatives with Anticancer Activity.

Sara P S P Moura, Silvia Marín, Ismael Rufino, Rita C Guedes, Marta Cascante, Jorge A R Salvador

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Molegro Data Modeller to Estimate CDK6 Inhibition.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sara P S P MouraLaboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0001-5791-6528
Silvia MarínDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0003-0693-2207
Ismael RufinoResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisboa, 1649-003 Lisboa, Portugal.ORCID 0000-0002-3718-3264
Rita C GuedesResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisboa, 1649-003 Lisboa, Portugal.ORCID 0000-0002-5790-9181
Marta CascanteDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-2062-4633
Jorge A R SalvadorLaboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0003-0779-6083

Funding

Agència de Gestió d'Ajuts Universitaris i de Recerca 2021 SGR 00350Centro de Investigación Biomédica en Red en Enfermedades hepáticas y digestivas CB17/04/00023European Regional Development Fund CENTRO-07-CT62-823 FEDER-002012Portuguese Foundation for Science and Technology 10.54499/LA/P/0058/2020Portuguese Foundation for Science and Technology 10.54499/UIDB/04539/2020Portuguese Foundation for Science and Technology 10.54499/UIDP/04539/2020Portuguese Foundation for Science and Technology RECI/QEQ-QFI/0168/2012Portuguese Foundation for Science and Technology REEQ/481/QUI/2006Portuguese Foundation for Science and Technology SFRH/BD/138674/2018Portuguese Foundation for Science and Technology UID/QUI/00313/2019
6 · The paper itself

Abstract

A series of novel carnosic acid

Indexed as

AbietanesAntineoplastic AgentsCell ProliferationCyclin-Dependent Kinase 6Drug DesignMolecular Docking SimulationUreaCell Cycle CheckpointsCell Line, TumorCyclin-Dependent Kinase 4Drug Screening Assays, AntitumorHCT116 CellsHumansReactive Oxygen SpeciesAbietanesAntineoplastic AgentsCDK4 protein, humanCDK6 protein, humanCyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6Reactive Oxygen SpeciessalvinUreaabietaneanticancer activitycarnosic acidCDK4CDK6cell cycle arrestditerpenoidsreactive oxygen species (ROS)urea derivatives

Identifiers

PMID39769100
PMCPMC11728001

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.