Evidence map›Paper›PMID 39769163›Full record

ArticleInternational journal of molecular sciences2024

Blocking the Sphingosine-1-Phosphate Receptor 2 (S1P

Ju-Hyun Lee, Jung-Eun Lee, Dong-Soon Im

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ju-Hyun LeeDepartment of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02446, Republic of Korea.
Jung-Eun LeeDepartment of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02446, Republic of Korea.
Dong-Soon ImDepartment of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02446, Republic of Korea.ORCID 0000-0001-8054-8946

Funding

National Research Foundation of Korea NRF-2023R1A2C2002380
6 · The paper itself

Abstract

The amount of sphingosine 1-phosphate (S1P) found in the synovial tissue of individuals with rheumatoid arthritis is five times greater than that in those with osteoarthritis. Our study aims to determine whether inhibiting S1P

Indexed as

Arthritis, ExperimentalMice, Inbred DBAMice, KnockoutSphingosine-1-Phosphate ReceptorsTh17 CellsAnimalsArthritis, RheumatoidCytokinesHumansMaleMicePyrazolesPyridinesSynovial MembraneTh1 CellsCytokinesJTE 013PyrazolesPyridinessphingosine-1-phosphate receptor-2, mouseSphingosine-1-Phosphate ReceptorsarthritisJTE-013rheumatoidS1P2sphingosine 1-phosphate

Identifiers

PMID39769163
PMCPMC11677552

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.