Evidence map›Paper›PMID 39769368›Full record

ArticleInternational journal of molecular sciences2024

The In Vitro Enhancement of Retinal Cell Viability via m

Gabriela Betlej, Ewelina Bator, Anna Koziorowska, Marek Koziorowski, Iwona Rzeszutek

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriela BetlejInterdisciplinary Centre for Preclinical and Clinical Research, College of Natural Sciences, University of Rzeszow, Werynia 2a, 36-100 Kolbuszowa, Poland.ORCID 0000-0003-0620-7195
Ewelina BatorInterdisciplinary Centre for Preclinical and Clinical Research, College of Natural Sciences, University of Rzeszow, Werynia 2a, 36-100 Kolbuszowa, Poland.ORCID 0000-0001-5510-7938
Anna KoziorowskaInterdisciplinary Centre for Preclinical and Clinical Research, College of Natural Sciences, University of Rzeszow, Werynia 2a, 36-100 Kolbuszowa, Poland.ORCID 0000-0003-1344-4033
Marek KoziorowskiInterdisciplinary Centre for Preclinical and Clinical Research, College of Natural Sciences, University of Rzeszow, Werynia 2a, 36-100 Kolbuszowa, Poland.ORCID 0000-0002-7468-6063
Iwona RzeszutekInterdisciplinary Centre for Preclinical and Clinical Research, College of Natural Sciences, University of Rzeszow, Werynia 2a, 36-100 Kolbuszowa, Poland.ORCID 0000-0001-6016-868X

Funding

Young Research Grant from University of Rzeszow NIG/30/2023
6 · The paper itself

Abstract

Degenerative retinal diseases can lead to blindness if left untreated. At present, there are no curative therapies for retinal diseases. Therefore, effective treatment strategies for slowing the progression of retinal diseases and thus improving patients' life standards are urgently needed. The present study aimed to assess the effect of sinusoidal electromagnetic field (EMF) (50 Hz, 1.3 mT) treatment for 15 and 30 min on spontaneously arising retinal pigment epithelial cells (ARPE-19) and retinal ganglion cells (RGC-5) and its short-term post-treatment significance. Our study indicated the beneficial impact of EMF treatment on the proliferative and migratory capacity of the tested cells. ARPE-19 and RGC-5 cells exposed to an EMF exhibited elevated levels of HO-1, increased N6-methyladenosine (m

Indexed as

AdenosineCell SurvivalDNA RepairElectromagnetic FieldsHeme Oxygenase-1Retinal Ganglion CellsRetinal Pigment Epithelium5-MethylcytosineCell LineCell ProliferationDNA DamageHumansMethylationMethyltransferasesRetinaRNA5-MethylcytosineAdenosineHeme Oxygenase-1MethyltransferasesMETTL3 protein, humanN-methyladenosineRNADNA damage repairelectromagnetic field (EMF)heme oxygenase (HO)retinaRNA methylation

Identifiers

PMID39769368
PMCPMC11677922

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.