Evidence map›Paper›PMID 39769381›Full record

ArticleInternational journal of molecular sciences2024

Delayed Tooth Development and the Impaired Differentiation of Stem/Progenitor Cells in Incisors from Type 2 Diabetes Mice.

Yoshifumi Kobayashi, Jia Huang, Brandon K Barnett, Carla Y Falcon, Paul A Falcon, Craig S Hirschberg, Daniel H Fine, Yi Ye, Emi Shimizu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yoshifumi KobayashiDepartment of Oral Biology, Rutgers School of Dental Medicine, Newark, NJ 07103, USA.
Jia HuangDepartment of Oral Biology, Rutgers School of Dental Medicine, Newark, NJ 07103, USA.
Brandon K BarnettDepartment of Endodontics, Rutgers School of Dental Medicine, Newark, NJ 07103, USA.
Carla Y FalconDepartment of Endodontics, Rutgers School of Dental Medicine, Newark, NJ 07103, USA.ORCID 0000-0002-4569-8452
Paul A FalconDepartment of Endodontics, Rutgers School of Dental Medicine, Newark, NJ 07103, USA.
Craig S HirschbergDepartment of Endodontics, Rutgers School of Dental Medicine, Newark, NJ 07103, USA.
Daniel H FineDepartment of Oral Biology, Rutgers School of Dental Medicine, Newark, NJ 07103, USA.ORCID 0000-0001-6242-6451
Yi YeBluestone Center for Clinical Research, New York University College of Dentistry, New York, NY 10010, USA.ORCID 0000-0002-1075-5584
Emi ShimizuDepartment of Oral Biology, Rutgers School of Dental Medicine, Newark, NJ 07103, USA.

Funding

Growth factors-induced dentinogenesisR01DE025885 · NIDCR · RBHS-SCHOOL OF DENTAL MEDICINE · PI SHIMIZU, EMI · 2016 to 2021
$2.1M
The novel functions of matrix metalloproteinase 13 supporting dentin-pulp reparative processesR56DE033709 · NIDCR · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI SHIMIZU, EMI · 2024 to 2024
$400k
Skyscan 1172 Ex-vivo MicroComputed Tomography SystemS10OD010751 · OD · NEW YORK UNIVERSITY · PI PARTRIDGE, NICOLA C · 2013 to 2013
$326k
NIDCR NIH HHS R01 DE025885NIDCR NIH HHS R56 DE033709NIH HHS 1R01DE025885-06A1S1NIH HHS S10 OD010751
6 · The paper itself

Abstract

Patients with diabetes mellitus (DM) have an increased risk of tooth decay caused by alterations in their tooth development and their oral environment, as well as a tendency to present with pulp infection due to compromised immune response. The present study analyzed the characteristic alterations in tooth development under DM conditions using incisors from

Indexed as

Cell DifferentiationDental PulpDiabetes Mellitus, Type 2IncisorOdontogenesisStem CellsAmeloblastsAnimalsDiabetes Mellitus, ExperimentalMaleMiceOdontoblastsameloblastdental pulp stem cellsdentinenamelodontoblastRNA-Seqtooth developmenttranscriptometype 2 diabetes

Identifiers

PMID39769381
PMCPMC11728242

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.