Evidence map›Paper›PMID 39769435›Full record

ArticleInternational journal of molecular sciences2024

LPS Disrupts Endometrial Receptivity by Inhibiting STAT1 Phosphorylation in Sheep.

Xing Fan, Jinzi Wei, Yu Guo, Juan Ma, Meiyu Qi, He Huang, Peng Zheng, Wenjie Jiang, Yuchang Yao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xing FanCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150038, China.
Jinzi WeiCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150038, China.
Yu GuoCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150038, China.
Juan MaCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150038, China.
Meiyu QiInstitute of Animal Husbandry, Heilongjiang Academy of Agricultural Sciences, Harbin 150086, China.
He HuangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150038, China.
Peng ZhengCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150038, China.ORCID 0000-0003-1234-8533
Wenjie JiangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150038, China.ORCID 0000-0002-3963-0857
Yuchang YaoCollege of Animal Science and Technology, Northeast Agricultural University, Harbin 150038, China.

Funding

National Natural Science Foundation of China 32172734
6 · The paper itself

Abstract

Uterine infections reduce ruminant reproductive efficiency. Reproductive dysfunction caused by infusion of Gram-negative bacteria is characterized by the failure of embryo implantation and reduced conception rates. Lipopolysaccharide (LPS), a major component of the outer membrane of Gram-negative bacteria, is highly abortogenic. In this study, the effects of LPS infusion on the endometrial receptivity of sheep were studied during three critical periods of embryo implantation. The results showed that LPS infusion on d12, d16, and d20 of pregnancy in vivo interfered with the expression of prostaglandins (PGs) and affected the expression of adhesion-related factors (

Indexed as

Embryo ImplantationEndometriumLipopolysaccharidesSTAT1 Transcription FactorAnimalsFemaleInterferon Type IPhosphorylationPregnancyPregnancy ProteinsProstaglandinsSheepSignal Transductioninterferon tauInterferon Type ILipopolysaccharidesPregnancy ProteinsProstaglandinsSTAT1 Transcription Factorembryo implantationendometrial receptivityLPSsheepSTAT1

Identifiers

PMID39769435
PMCPMC11678167

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.