Evidence mapPaperPMID 39769446Full record

ArticleInternational journal of molecular sciences2024

Circulating Brain-Reactive Autoantibody Profiles in Military Breachers Exposed to Repetitive Occupational Blast.

Shawn G Rhind, Maria Y Shiu, Oshin Vartanian, Catherine Tenn, Ann Nakashima, Rakesh Jetly, Zhihui Yang, Kevin K Wang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shawn G RhindDefence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada.ORCID 0000-0003-2300-0620
Maria Y ShiuDefence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada.
Oshin VartanianDefence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada.
Catherine TennDefence Research and Development Canada, Suffield Research Centre, Medicine Hat, AB T1A 8K6, Canada.
Ann NakashimaDefence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada.
Rakesh JetlyThe Institute of Mental Health Research, University of Ottawa, Royal Ottawa Hospital, Ottawa, ON K1Z 7K4, Canada.ORCID 0000-0001-6610-9365
Zhihui YangMcKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA.
Kevin K WangMcKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA.

Funding

Department of National Defence NA
6 · The paper itself

Abstract

Military breachers are routinely exposed to repetitive low-level blast overpressure, placing them at elevated risk for long-term neurological sequelae. Mounting evidence suggests that circulating brain-reactive autoantibodies, generated following CNS injury, may serve as both biomarkers of cumulative damage and drivers of secondary neuroinflammation. In this study, we compared circulating autoantibody profiles in military breachers (

Indexed as

AutoantibodiesBlast InjuriesGlial Fibrillary Acidic ProteinImmunoglobulin GMilitary PersonnelMyelin Basic ProteinAdultBiomarkersBrainFemaleHumansImmunoglobulin MMaleMiddle AgedOccupational ExposureAutoantibodiesBiomarkersGFAP protein, humanGlial Fibrillary Acidic ProteinImmunoglobulin GImmunoglobulin MMyelin Basic Proteinanti-GFAPanti-MBPanti-pituitaryautoimmune antibodiesblastblood–brain barrierbrain injurybreacherinflammationrepetitive subconcussive head impacts

Identifiers

PMID39769446
PMCPMC11728191

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.