Evidence map›Paper›PMID 39770027›Full record

ArticleMolecules (Basel, Switzerland)2024

Aged Garlic Extract (AGE) and Its Constituent S-Allyl-Cysteine (SAC) Inhibit the Expression of Pro-Inflammatory Genes Induced in Bronchial Epithelial IB3-1 Cells by Exposure to the SARS-CoV-2 Spike Protein and the BNT162b2 Vaccine.

Jessica Gasparello, Chiara Papi, Giovanni Marzaro, Alberto Macone, Matteo Zurlo, Alessia Finotti, Enzo Agostinelli, Roberto Gambari

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jessica GasparelloDepartment of Life Sciences and Biotechnology, Ferrara University, 44121 Ferrara, Italy.
Chiara PapiDepartment of Life Sciences and Biotechnology, Ferrara University, 44121 Ferrara, Italy.ORCID 0000-0001-9242-1766
Giovanni MarzaroDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.ORCID 0000-0002-5892-5992
Alberto MaconeDepartment of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-0455-1400
Matteo ZurloDepartment of Life Sciences and Biotechnology, Ferrara University, 44121 Ferrara, Italy.
Alessia FinottiDepartment of Life Sciences and Biotechnology, Ferrara University, 44121 Ferrara, Italy.ORCID 0000-0002-7638-515X
Enzo AgostinelliDepartment of Sensory Organs, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-2508-8868
Roberto GambariDepartment of Life Sciences and Biotechnology, Ferrara University, 44121 Ferrara, Italy.ORCID 0000-0001-9205-6033

Funding

CARIPARO Foundation MARZ_CARIVARI20_01 C94I20002500007MUR-FISR FISR2020IP_04128
6 · The paper itself

Abstract

Garlic (

Indexed as

COVID-19 Drug TreatmentCysteineCytokine Release SyndromeGarlicInterleukinsPlant ExtractsSpike Glycoprotein, CoronavirusAnti-Inflammatory AgentsBNT162 VaccineBronchiCell LineCOVID-19Epithelial CellsGene Expression RegulationHumansRespiratory MucosaAnti-Inflammatory AgentsBNT162 VaccineCysteineInterleukinsPlant ExtractsS-allylcysteineSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2garlicnatural productsNF-κBpro-inflammatory genesToll-like receptor 4

Identifiers

PMID39770027
PMCPMC11677098

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.