Evidence map›Paper›PMID 39770816›Full record

ReviewMicroorganisms2024

Depression Treatment: Is There a Role for Botulinum Toxin Type A?

Carmen Rodríguez-Cerdeira, Westley Eckhardt

Abstract readReview
In one paragraph

Review in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carmen Rodríguez-CerdeiraDepartment of University Program for Seniors, University of Vigo, E.E. Industrial Rúa Torrecedeira 86, Vigo Campus, 36201 Vigo, Spain.ORCID 0000-0001-9939-0771
Westley EckhardtDepartment of University Program for Seniors, University of Vigo, E.E. Industrial Rúa Torrecedeira 86, Vigo Campus, 36201 Vigo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to determine whether botulinum toxin type A injected into the muscles of the upper third of the face has antidepressant effects in patients diagnosed with depression. Studies seeking a relationship between botulinum toxin type A and its antidepressant effects were considered in this review. All studies concluded that the facial expression muscles present positive feedback to the brain and enhance mood states. Botulinum toxin when applied to the corrugator and procerus muscles has an antidepressant effect.

Indexed as

antidepressantbotulinum toxin type Adepressionsystematic review

Identifiers

PMID39770816
PMCPMC11677039

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.