Evidence map›Paper›PMID 39770932›Full record

ArticleNutrients2024

From Tea to Functional Foods: Exploring

Xin Dong, Zhi Wang, Yao Fu, Yuxin Tian, Peifeng Xue, Yuewu Wang, Feiyun Yang, Guojing Li, Ruigang Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Potential of Alkaloids fromCurrent issues in molecular biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xin DongKey Laboratory of Plants Adversity Adaptation and Genetic Improvement in Cold and Arid Regions of Inner Mongolia, Inner Mongolia Agricultural University, Hohhot 010018, China.
Zhi WangDepartment of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot 010110, China.
Yao FuDepartment of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot 010110, China.
Yuxin TianDepartment of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot 010110, China.
Peifeng XueDepartment of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot 010110, China.
Yuewu WangDepartment of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot 010110, China.
Feiyun YangKey Laboratory of Plants Adversity Adaptation and Genetic Improvement in Cold and Arid Regions of Inner Mongolia, Inner Mongolia Agricultural University, Hohhot 010018, China.
Guojing LiKey Laboratory of Plants Adversity Adaptation and Genetic Improvement in Cold and Arid Regions of Inner Mongolia, Inner Mongolia Agricultural University, Hohhot 010018, China.
Ruigang WangKey Laboratory of Plants Adversity Adaptation and Genetic Improvement in Cold and Arid Regions of Inner Mongolia, Inner Mongolia Agricultural University, Hohhot 010018, China.

Funding

IMAU & Inner Mongolia Autonomous Region University Science and Technology Innovation Team NMGlRT2222 & BR22-13-05
6 · The paper itself

Abstract

background

methodsForty-eight female Sprague-Dawley rats were randomly assigned to six groups (

resultsThe results demonstrated that CM extract effectively suppressed synovial inflammation in CIA rats, reducing joint degradation. CM's anti-inflammatory effects were mediated through the TNF signaling pathway, modulating glycerophospholipid and amino acid metabolism, including reduced levels of tryptophan, LysoPC, and asparagine. Molecular docking identified scutellarin and apigenin as key bioactive compounds. Additionally, immunofluorescence analysis revealed CM's therapeutic effects via TNF signaling inhibition and suppression of M1 macrophage polarization.

conclusionsThese findings highlight the therapeutic potential of CM for RA and support its development as a functional food or pharmaceutical product.

Indexed as

Anti-Inflammatory AgentsArthritis, ExperimentalArthritis, RheumatoidFunctional FoodPlant ExtractsRats, Sprague-DawleyAnimalsFemaleMolecular Docking SimulationNetwork PharmacologyRatsSignal TransductionTeaAnti-Inflammatory AgentsPlant ExtractsTeaCaryopteris mongolica Bungeinflammatory responsemechanismmetabolomicsrheumatoid arthritistranscriptomics

Identifiers

PMID39770932
PMCPMC11680032

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.