ArticleNutrients2024
The Camden Study-A Pregnancy Cohort Study of Pregnancy Complications and Birth Outcomes in Camden, New Jersey, USA.
Stephanie Shiau, Xinhua Chen, Ayana April-Sanders, Ellen C Francis, Shristi Rawal, Megan Hansel, Kehinde Adeyemi, Zorimar Rivera-Núñez, Emily S Barrett
Abstract read
In one paragraphArticle in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors.
Stephanie ShiauDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.ORCID 0000-0003-2944-3406 Xinhua ChenDepartment of Obstetrics/Gynecology, Rowan-Virtua School of Osteopathic Medicine, Rowan University, Stratford, NJ 08084, USA.ORCID 0000-0003-0550-3662 Ayana April-SandersDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.ORCID 0000-0003-3341-4464 Ellen C FrancisDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.
Shristi RawalDepartment of Clinical and Preventive Nutrition Sciences, School of Health Professions, Rutgers University, Newark, NJ 07107, USA.ORCID 0000-0003-2587-4022 Megan HanselDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.
Kehinde AdeyemiDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.
Zorimar Rivera-NúñezDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.
Emily S BarrettDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.
Funding
Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4MOXIDATIVE STRESS, ANTIOXIDANT STATUS &PREGNANCY OUTCOMER01HD038329 · NICHD · UNIV OF MED/DENT NJ-SCH OSTEOPATHIC MED · PI SCHOLL, THERESA O. · 2000 to 2005
$3.5MMaternal inflammation in relation to offspring epigenetic aging and neurodevelopmentR01HD111550 · NICHD · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Stephanie Shiau · 2023 to 2026
$2.6MFatty acids-mediated inflammation and ethnic disparity in pregnancy outcomeR01MD007828 · NIMHD · ROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED · PI CHEN, XINHUA · 2013 to 2017
$1.9MLEAD MOBILIZATION &BONE TURNOVER IN PREGNANCY/LACTATIONR01ES007437 · NIEHS · UNIV OF MED/DENT NJ-SCH OSTEOPATHIC MED · PI SCHOLL, THERESA O. · 1996 to 2000
$535kVitamin D status in pregnant womenR21HD058128 · NICHD · UNIV OF MED/DENT NJ-SCH OSTEOPATHIC MED · PI SCHOLL, THERESA O. · 2008 to 2009
$429kCardiovascular risk factors and preterm deliveryR21HD061763 · NICHD · UNIV OF MED/DENT NJ-SCH OSTEOPATHIC MED · PI CHEN, XINHUA · 2009 to 2010
$427kImpaired Glucose Challenge Test & Maternal-Fetal OutcomesR21DK078865 · NIDDK · UNIV OF MED/DENT NJ-SCH OSTEOPATHIC MED · PI CHEN, XINHUA · 2007 to 2008
$425kADOLESCENT PREGNANCY--NUTRITION, GROWTH, AND OUTCOMEER01HD018269 · NICHD · UNIV OF MED/DENT NJ-SCH OSTEOPATHIC MED · PI SCHOLL, THERESA O. · 1985 to 1999
–NICHD NIH HHS R01 HD038329NICHD NIH HHS R01 HD111550NICHD NIH HHS R21 HD058128NICHD NIH HHS R21 HD061763NIDDK NIH HHS R21 DK078865NIEHS NIH HHS P30 ES005022NIH HHS MD007828NIH HHS P30ES005022NIH HHS R01ES007437NIH HHS R01HD018269NIH HHS R01HD038329NIH HHS R21DK078865NIH HHS R21HD058128NIH HHS R21HD061763NIMHD NIH HHS R01 MD007828
6 · The paper itselfAbstract
backgroundPregnancy is a unique stage of the life course characterized by trade-offs between the nutritional, immune, and metabolic needs of the mother and fetus. The Camden Study was originally initiated to examine nutritional status, growth, and birth outcomes in adolescent pregnancies and expanded to study dietary and molecular predictors of pregnancy complications and birth outcomes in young women.
methodsFrom 1985-2006, 4765 pregnant participants aged 12 years and older were recruited from Camden, NJ, one of the poorest cities in the US. The cohort reflects a population under-represented in perinatal cohort studies (45% Hispanic, 38% non-Hispanic Black, 17% White participants; 98% using Medicaid in pregnancy). Study visits, including questionnaires, dietary assessments, and biospecimen collection, occurred in early and late pregnancy as well as at delivery. Medical records were abstracted, and a subset of mothers and infants participated in a six-week postpartum visit.
resultsFindings from the Camden Study have added to the understanding of adolescent and young adult maternal health and perinatal outcomes. These include associations of adolescent linear growth while pregnant with smaller neonatal birth size, low dietary zinc intake in early pregnancy with increased risk of delivery <33 gestational weeks, and higher circulating fatty acid levels with greater insulin resistance. More recent analyses have begun to unpack the biochemical pathways in pregnancy that may be shaped by race as an indicator of systemic racism.
conclusionsThe Camden Study data and biorepositories are well-positioned to support future research aimed at better understanding perinatal health in under-represented women and infants. Linkages to subsequent health and administrative records and the potential for recontacting participants over 18-39 years after initial participation may provide key insights into the trajectories of maternal and child health across the life course.
Indexed as
Health Status DisparitiesPerinatal DeathPregnancy ComplicationsAdolescentAdultAsian PeopleBlack PeopleChildFemaleGestational AgeHispanic or LatinoHumansMaternal AgeNutritional StatusPostpartum PeriodPregnancygestational diabeteslife coursematernal and child healthnutritionperinatal epidemiologypostpartumpregnancy
Identifiers
PMID39770993
PMCPMC11680084
What Socratic holds
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