Evidence mapPaperPMID 39771535Full record

ReviewPharmaceutics2024

Polycystic Ovary Syndrome and the Potential for Nanomaterial-Based Drug Delivery in Therapy of This Disease.

Mingqin Shi, Xinyao Li, Liwei Xing, Zhenmin Li, Sitong Zhou, Zihui Wang, Xuelian Zou, Yuqing She, Rong Zhao, Dongdong Qin

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mingqin ShiFirst Clinical Medical College, Yunnan University of Chinese Medicine, Kunming 650500, China.
Xinyao LiSchool of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China.
Liwei XingFirst Clinical Medical College, Yunnan University of Chinese Medicine, Kunming 650500, China.
Zhenmin LiSchool of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130021, China.ORCID 0009-0001-5437-7175
Sitong ZhouSchool of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China.
Zihui WangSecond Clinical Medical College, Yunnan University of Chinese Medicine, Kunming 650500, China.
Xuelian ZouSchool of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China.
Yuqing SheSchool of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China.
Rong ZhaoFirst Clinical Medical College, Yunnan University of Chinese Medicine, Kunming 650500, China.
Dongdong QinSchool of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China.ORCID 0000-0002-2005-8408

Funding

Applied Basic Research Programs of Science and Technology Commission Foundation of Yunnan Province 202301AS070053Key Laboratory of Traditional Chinese Medicine for Prevention and Treatment of Neuropsychi-atric Diseases Yunnan Provincial Department of EducationNational Natural Science Foundation of China 82160923National Natural Science Foundation of China 82374425National Natural Science Foundation of China 82460974Scientific Research Projects for High-level Talents of Yunnan University of Chinese Medicine 2019YZG01Young Top-Notch Talent in 10,000 Talent Program of Yunnan Province YNWR-QNBJ-2019-235Yunnan Key Laboratory of Dai and Yi Medicines ,Yunnan University of Chinese Medicine 2024SS24007Yunnan Province Innovation Team of Prevention and Treatment for Brain Diseases With Acu-puncture and Tuina 202405AS350007
6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is the predominant endocrine disorder among women of reproductive age and represents the leading cause of anovulatory infertility, which imposes a considerable health and economic burden. Currently, medications used to treat PCOS can lead to certain adverse reactions, such as affecting fertility and increasing the risk of venous thrombosis. Drug delivery systems utilizing nanomaterials, characterized by prolonged half-life, precision-targeted delivery, enhanced bioavailability, and reduced toxicity, are currently being employed in the management of PCOS. This innovative approach is gaining traction as a favored strategy for augmenting the therapeutic efficacy of medications. Consequently, this paper discusses the roles of nanoparticles, nanocarriers, and targeted ligands within nanomaterial-based drug delivery systems, aiming to identify optimal methodologies for treating PCOS using nanomaterials. Additionally, prospective research avenues concerning nanomaterial-based delivery systems in the context of PCOS, as well as the implications of existing insights on the advancement of novel therapies for PCOS, are highlighted.

Indexed as

nanoparticlesnovel drug delivery systemspolycystic ovary syndrometherapeutic efficacy

Identifiers

PMID39771535
PMCPMC11678845

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.