ReviewCurrent medicinal chemistry2025
The Role of Lipids in Atherosclerosis: Focus on Molecular Biology Mechanisms and Therapeutic Approaches.
Review in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Association between remnant cholesterol inflammation Index and in-hospital New-onset atrial fibrillation in patients with ST-segment elevation myocardial infarction.Frontiers in cardiovascular medicine · 2026Article
- Disrupted Lipid Metabolism Aggravates Ischemic Brain Injury: Targeting FDFT1 for Stroke Therapy.Molecular neurobiology · 2025Article
- Jianpi Qutan Decoction improves hepatic lipid metabolism in atherosclerosis mice via PPARα-CPT1α pathway regulation.Hereditas · 2025Article
- Unraveling the Dyslipidemic Landscape in Moyamoya Disease: OxLDL as a Key Biomarker.CNS neuroscience & therapeutics · 2025Article
- The Link between Lipids and Inflammation: Focus on Targeting Sialidase Activity as a Novel Strategy for Anti-Atherosclerotic Therapy.Current medicinal chemistry · 2025Article
- Transcriptional profiling identification of inflammatory signaling pathways in ulcerative colitis.PloS one · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atherosclerosis is a complex vascular disease characterized by the buildup of lipids, inflammatory cells and fibrous components in arterial walls leading to plaque formation and potential thrombotic events like myocardial infarction and strokes. Recently, there has been research on the roles of various types of lipids such as low-density lipoprotein (LDL) cholesterol, oxidized LDL (oxLDL) cholesterol and small dense LDL (sdLDL) in the onset and progression of atherosclerosis. These lipoproteins contribute to dysfunction and inflammation processes that play a role in the development and instability of plaques. Moreover, certain enzymes and proteins linked to lipids have been associated with atherosclerosis highlighting the complex interplay between lipid metabolism and inflammation in this disease. This review delves into the mechanisms behind atherosclerosis focusing on the involvement of lipids, enzymes and regulatory proteins. Additionally, it will also discuss present treatments as well as new therapeutic approaches that target these molecular mechanisms with the goal of advancing our knowledge about atherosclerosis and guiding future treatment strategies.
Indexed as
Identifiers
39773041What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.