ArticleBMC surgery2025
Effect of anastomotic reinforcement with barded suture on anastomotic leakage prevention following laparoscopic low anterior resection for rectal cancer: a retrospective single-center study.
Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comprehensive evaluation of reinforcement strategies for anastomotic leak prevention in rectal cancer surgery: an umbrella review of meta-analyses.Updates in surgery · 2025Pooled it
- Comparative efficacy of reinforced suturing, transanal drainage tube, and no additional intervention in preventing anastomotic leakage after rectal cancer surgery: a network meta-analysis.International journal of colorectal disease · 2026Article
- Achieving the perfect end-to-end single-stapled anastomosis in low anterior resection for rectal cancer: technical aspects.Annals of coloproctology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
backgroundAnastomotic leakage (AL) is a serious complication that may occur following the double stapling technique (DST). The study aims to investigate the efficacy of anastomotic reinforcement using barbed sutures in preventing AL after laparoscopic low anterior resection (LAR) for rectal cancer.
methodsDuring the period from November 1, 2018 to November 1, 2023, a total of 725 consecutive patients who had underwent laparoscopic LAR for rectal cancer were enrolled in this study. The patients were divided into two groups: the continuous barbed suture reinforcement group (N = 296) and the control group (N = 429). Inter-group comparisons were used the chi-squared test, Fisher's exact test, and nonparametric tests. Independent risk or protective factors for AL were analyzed using the multivariate logistic regression.
resultsAmong the 725 patients enrolled in this study, 24 patients (3.3%) were diagnosed with AL following surgery. The incidence of AL was lower in the reinforcement group when compared with the control group (1.4% vs. 4.7%, P = 0.014). In multivariate regression analyses, the neoadjuvant therapy (OR = 11.994, P < 0.01), tumor location (OR = 5.306, P = 0.015), anastomosis bleeding (OR = 58.822, P < 0.01), and number of staple firings used (≥ 3) (OR = 24.752, P < 0.01) were independent risk factors for AL, whereas the defunctioning stoma (OR = 0.051, P < 0.01) and reinforcing sutures (OR = 0.054, P = 0.001) were independent protective factors for AL in this study. No statistically significant differences were found in 36-item short-Form (SF-36) when evaluating the quality of patient's life between the two groups.
conclusionsLaparoscopic continuous barbed suture reinforcement of anastomosis could reduce the incidence of AL without affecting the quality-of-life following LAR. Further popularization of this approach in clinical is warranted.
trial registrationRetrospectively registered.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.