Evidence mapPaperPMID 39773792Full record

Observational studyBMJ open2025

Epidemiological features of uterine fibroid-associated imaging changes in Chinese women of reproductive age: a retrospective study.

Lijun Zhang, Fan Xu, Yanyan Huang, Wei Xu, Yang Pu, Ke Chen, Bingqian Zhou, Ruoyan Gong, Xueyao Su, Jiayuan Zhang and 1 more

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lijun ZhangSchool of Public Health, Chongqing Medical University, Chongqing, China.ORCID http://orcid.org/0000-0002-4425-8738
Fan XuDepartment of Obstetrics and Gynecology, Nanchong Central Hospital Affiliated to North Sichuan Medical College, Nanchong, Sichuan, China.
Yanyan HuangSchool of Public Health, Chongqing Medical University, Chongqing, China.ORCID http://orcid.org/0000-0001-8878-6180
Wei XuSchool of Public Health, Chongqing Medical University, Chongqing, China.
Yang PuSchool of Public Health, Chongqing Medical University, Chongqing, China.
Ke ChenDepartment of Health Management Center, Nanchong Central Hospital Affiliated to North Sichuan Medical College, Nanchong, Sichuan, China.
Bingqian ZhouDepartment of Health Management Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ruoyan GongSchool of Public Health, Chongqing Medical University, Chongqing, China.
Xueyao SuSchool of Public Health, Chongqing Medical University, Chongqing, China.
Jiayuan ZhangCollege of Biomedical Engineering, Chongqing Medical University, Chongqing, China.
Qiuling ShiSchool of Public Health, Chongqing Medical University, Chongqing, China qshi@cqmu.edu.cn.ORCID http://orcid.org/0000-0003-0660-3809

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate uterine fibroid (UF)-associated imaging changes, and their prevalence, incidence and potential risk factors in the Chinese population.

designThis was a retrospective observational study using health examination data.

settingA physical examination centre in Nanchong, China, between October 2017 and December 2020.

participantsA total of 33 915 Chinese women older than 15 years of age underwent uterine imaging during the study period. PRIMARY AND SECONDARY OUTCOME MEASURES: This study identified entries of UF-associated imaging changes through a two-round expert consultation and calculated prevalence and incidence of UF-associated imaging changes. Logistic regression estimated the association (OR, 95% CI of body mass index, high blood pressure (HBP), blood lipid profile, and fasting blood glucose level) with UF-associated imaging changes. Age-stratified (≤40 years and >40 years) risks were ascertained.

resultsBesides the entry 'Potential UF', 17 other entries of UF-associated imaging changes screened by the expert consultation were included, involving a total of 46 864 records (n=33 915), and crude prevalence=25.18%; crude incidence density/1000-woman-years=63.28. Incidence and prevalence increased with age during reproductive age (15-49 years) and decreased thereafter. The greatest burden was in women aged 40-54 years, the prevalence was 38.60%-45.38% and the incidence was 14.73%-17.96%. In the incident younger population (age ≤40 years), overweight (OR: 1.48, 95% CI 1.03 to 2.14) and HBP (OR: 2.16, 95% CI 1.10 to 4.24) were associated with a higher risk for UF-associated imaging changes; in the >40 years group, no association was observed.

conclusionUF incidence and prevalence in Asians were higher than previously reported, showed age-related increase in reproductive age, and UF incidence increased with overweight and HBP in ≤40-year-old participants. Variation in UF burden and factors with higher risk noted in different age ranges, and the correlations identified in younger women make it possible for early preventive measures for women with a higher risk of UF.

Indexed as

LeiomyomaUterine NeoplasmsAdolescentAdultBody Mass IndexChinaEast Asian PeopleFemaleHumansIncidenceMiddle AgedPrevalenceRetrospective StudiesRisk FactorsYoung AdultChinaEPIDEMIOLOGYGynaecological oncologyPREVENTIVE MEDICINERetrospective Studies

Identifiers

PMID39773792
PMCPMC11749307

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.