Trial reportScientific reports2025
Efficacy of home based computerized adaptive cognitive training in patients with post stroke cognitive impairment: a randomized controlled trial.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effectiveness of technology-assisted cognitive interventions for post-stroke cognitive impairment: a systematic review and meta-analysis.Systematic reviews · 2026Pooled it
- Digital Interventions for Cognitive Dysfunction in Patients With Stroke: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Effects of Digital Cognitive Rehabilitation on Functional Performance After Stroke: A Systematic Review and Meta-Analysis of ADL and IADL Outcomes.Healthcare (Basel, Switzerland) · 2026Review
- Article
- Longitudinal plasma interleukin-6 and post-stroke cognitive outcomes: The Stroke-IMPaCT study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Article
- The CARE study protocol: game-based cognitive assessment via recreational engagement in patients with mild cognitive impairment in India.BMC geriatrics · 2026Article
- Epigenetic regulation of post-stroke cognitive impairment by gut microbiota and their metabolites.Frontiers in cellular and infection microbiology · 2026Review
- Limited Transfer of Working Memory Training to Instrumental Activities of Daily Living in Chronic Stroke Survivors: A Randomized Controlled Trial.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025Article
- Gamification Strategies in Digital Health Interventions for Attention Rehabilitation in Stroke Survivors: A Systematic Review.Journal of multidisciplinary healthcare · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Post-stroke cognitive impairment is a common consequence of stroke, characterized by deficits in language, cognitive functioning, functional abilities. Innovative technological approaches, such as computerized cognitive retraining, offer promising strategies for mitigating the cognitive challenges. Despite their potential, the impact of these interventions on neuropsychological function and daily living capabilities has poor outcomes. In this randomized controlled trial (RCT), we assessed the effectiveness of a 4-week, remotely-delivered, multi-domain, computer-adaptive cognitive retraining (CACT) program in patients with post-cognitive cognitive impairment. Fifty male participants were randomly assigned to either the experimental group, which underwent the CACT program tailored to individual performance levels, or an active control group that received standard care. The evaluation focused on neuropsychological functions such as attention, memory, and executive processes, alongside daily living skills. Results indicated that participants in the CACT group exhibited notable improvements in several cognitive areas, including processing speed, category fluency, and visual confrontation naming, when compared to the control group. Nonetheless, enhancements in functional abilities, encompassing basic and instrumental activities of daily living (ADL), were minimal, with no significant changes reported post-intervention. This study demonstrates that CACT effectively improves cognitive functions in patients with post-stroke cognitive impairment during the spontaneous recovery period, suggesting that training patients at their optimal performance levels can lead to meaningful cognitive benefits. These findings are specific to patients recovering from stroke-induced cognitive deficits and highlight the need for further research to generalize these results to other populations with vascular cognitive impairment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.