ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025
MRI-based endplate bone quality scores outperform vertebral bone quality scores in predicting adjacent segment disease following transforaminal lumbar interbody fusion.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The trial behind it
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Who cites it
5 citing papers in PubMed.
- Development and validation of explainable machine learning models to predict the risk of adjacent segment disease after lumbar fusion surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Sarcopenia, paraspinal muscle degeneration, and bone quality as prognostic factors for adjacent segment degeneration or disease after lumbar fusion: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Endplate Bone Quality Assessment for Preoperative Planning and Patient-Specific Implementation in Lumbar Spine Surgery.Journal of clinical medicine · 2026Article
- Comparing the Prognostic Utility of Vertebral and Endplate Bone Quality Scores for Cage Subsidence Following Single-Level Anterior Cervical Discectomy and Fusion: A Retrospective Analysis.Orthopaedic surgery · 2026Article
- Research on the predictive efficacy of MRI-based endplate bone quality and vertebral body bone quality scores for adjacent segment degeneration after lumbar spinal fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
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Authors and funding
10 authors.
Funding
Abstract
purposeThis study aims to (1) evaluate whether the endplate bone quality (EBQ) scores can independently predict adjacent segment disease (ASD); and (2) judge the predictive value of EBQ compared to vertebral bone quality (VBQ) for ASD after single-level transforaminal lumbar interbody fusion (TLIF).
methodsA single-center retrospective analysis was conducted of patients undergoing single-level TLIF for degenerative spinal disease from 2014 to 2020. Demographic, surgery, and radiographic data were collected. Logistic regression was used to identify independent risk factors for ASD. Furthermore, a receiver operating curve (ROC) analysis was conducted to evaluate the predictive efficacy of the EBQ score and VBQ score.
resultsThe rate of ASD was 16.4% at a minimum 24-month follow-up. Significant risk factors for ASD were higher VBQ score (OR = 3.418, 95%CI: 1.297-9.008, P = 0.013), higher EBQ score (OR = 2.469, 95%CI: 1.085-5.621, P = 0.031), and higher adjacent segment Pfirrmann grade (OR = 2.866, 95%CI: 1.765-4.653, P<0.001). The diagnostic accuracy of VBQ and EBQ for distinguishing ASD were 0.806 (95%CI: 0.728-0.883) and 0.835 (95%CI: 0.757-0.912). The optimal threshold of VBQ scores was 2.926 (sensitivity: 90.6%, specificity: 62.0%) and of EBQ was 3.511 (sensitivity: 90.6%, specificity: 71.8%).
conclusionHigher VBQ and EBQ scores are both independent risk factors of ASD after single-segment TLIF surgery, and EBQ scores perform better in predicting ASD. When EBQ > 3.511, there is a considerable risk of ASD.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.